1467-16-9 Usage
Description
Imidazole hydrochloride is an organic compound with the chemical formula C3H7N2·HCl. It is a white powder and is a useful research chemical due to its versatile properties and applications in various fields.
Uses
Used in Research and Development:
Imidazole hydrochloride is used as a research chemical for various scientific studies and experiments. It plays a crucial role in understanding different biological processes and chemical reactions.
Used in Double Immunohistochemistry:
Imidazole hydrochloride is used as a reagent in double immunohistochemistry to determine the activity of octopine dehydrogenase (ODH) in Mytilus galloprovincialis. This application helps researchers study the enzyme's role in the organism and its potential implications in various biological processes.
Used in Human In Vitro Fertilization Studies:
Imidazole hydrochloride is used as a reagent to study the cytoskeletal features during in vitro fertilization after intracytoplasmic sperm injection (ICSI) among humans. This application aids in understanding the cellular changes and mechanisms involved in successful fertilization and embryo development.
Used in Synthesis of Monitoring Probes:
Imidazole hydrochloride is used as a reagent in the synthesis of a probe for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene expression in rodents. This application is essential for tracking and studying the activity of the virus in experimental models, which can contribute to the development of antiviral treatments and therapies.
Used in Pharmaceutical Industry:
Imidazole hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical properties make it a valuable component in the development of new drugs and medications.
Used in Chemical Synthesis:
Imidazole hydrochloride is used as a reagent in various chemical synthesis processes, including the production of dyes, pigments, and other specialty chemicals. Its versatility and stability make it a popular choice for researchers and chemists in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 1467-16-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,6 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1467-16:
(6*1)+(5*4)+(4*6)+(3*7)+(2*1)+(1*6)=79
79 % 10 = 9
So 1467-16-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H4N2.ClH/c1-2-5-3-4-1;/h1-3H,(H,4,5);1H
1467-16-9Relevant articles and documents
The influence of hydrogen-bond defects on the properties of ionic liquids
Peppel, Tim,Roth, Christian,Fumino, Koichi,Paschek, Dietmar,Koeckerling, Martin,Ludwig, Ralf
, p. 6661 - 6665 (2011)
Counterintuitive: The preformation of ion pairs can explain the low melting points of imidazolium-based ionic liquids (ILs) and the resulting expanded range of working temperatures. This quasi-ion-pair formation is possible for ILs having cations with only one interaction site leading to local and directional hydrogen bonds with the corresponding anion (see structure; O red, N blue, F green, S yellow). Copyright
Solvent-freeN-Boc deprotection byex situgeneration of hydrogen chloride gas
De Borggraeve, Wim M.,Gilles, Philippe,Van Mileghem, Seger,Verschueren, Rik H.
supporting information, p. 5782 - 5787 (2021/07/12)
An efficient, scalable and sustainable method for the quantitative deprotection of thetert-butyl carbamate (N-Boc) protecting group is described, using down to near-stoichiometric amounts of hydrogen chloride gas in solvent-free conditions. We demonstrate theex situgeneration of hydrogen chloride gas from sodium chloride and sulfuric acid in a two-chamber reactor, introducing a straightforward method for controlled and stoichiometric release of HCl gas. The solvent-free conditions allow deprotection of a wide variety ofN-Boc derivatives to obtain the hydrochloride salts in quantitative yields. The procedure obviates the need for any work-up or purification steps providing an uncomplicated green alternative to standard methods. Due to the solvent-free, anhydrous conditions, this method shows high tolerance towards acid sensitive functional groups and furnishes expanded functional group orthogonality.
A Simple synthesis of sugar nucleoside diphosphates by chemical coupling in water
Tanaka, Hidenori,Yoshimura, Yayoi,Jürgensen, Malene R.,Cuesta-Seijo, Jose A.,Hindsgaul, Ole
, p. 11531 - 11534 (2013/01/15)
Sugar nucleotides made easy: The new reagent ImIm , which is formed in-situ in water, is shown to activate nucleoside 5'-phosphates to their imidazolides, these can subsequently couple with sugar-1-phosphates; the whole procedure takes place in water. This truly simple method yields a crude product mixture that can be used directly as a source of donors for glycosyltransferase- mediated oligsaccharide synthesis. In the scheme, B stands for the nucleobases U, A, or G. Copyright
