1470067-73-2Relevant articles and documents
In vivo and in vitro effect of androstene derivatives as 5α-reductase type 1 enzyme inhibitors
Bratoeff, Eugene,Sanchez, Araceli,Arellano, Yazmin,Heuze, Yvonne,Soriano, Juan,Cabeza, Marisa
, p. 1247 - 1254 (2013)
The aim of these studies was to synthesize twelve ester derivatives of dehydroepiandrosterone with therapeutic potential. The effect of 1-12 was demonstrated in the flank organs of gonadectomized hamsters treated with testosterone and the synthesized ster
Cytotoxic effect of novel dehydroepiandrosterone derivatives on different cancer cell lines
Garrido, Mariana,Cabeza, Marisa,Cortés, Francisco,Gutiérrez, José,Bratoeff, Eugene
, p. 301 - 311 (2013/10/01)
The aim of this study was to determine the cytotoxic effect of human cancer cells on three series of novel dehydroepiandrosterone derivatives containing triazole or pyrazole rings at C-17 and an ester moiety at C-3 of the androstane skeleton. The panel ca