83205-52-1

Basic information

• Product Name: 3β-benzoyloxy-androst-5-en-17-one
• CAS NO: 83205-52-1
• Molecular Weight: 392.538
• Mol File: 83205-52-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3β-benzoyloxy-androst-5-en-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-benzoyloxy-androst-5-en-17-one(83205-52-1)
• EPA Substance Registry System: 3β-benzoyloxy-androst-5-en-17-one(83205-52-1)

Safety Data

• Hazardous Substances Data: 83205-52-1(Hazardous Substances Data)

Upstream product

• 897-01-8 (3S,8R,9S,10R,13S,14S)-3-Chloro-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-17-one 
• 65-85-0 benzoic acid 
• 979-02-2 16-dehydropregnenolone acetate 
• 23549-24-8 3β-acetoxy-20-hydroxyiminopregna-5,16-diene 
• 853-23-6 prasterone acetate 
• 53-43-0 dehydroepiandrosterone 
• 94618-80-1 N-oxy methyl-imino-17 benzoyl-3β androstene-4 
• 108-24-7 acetic anhydride 
• 98-88-4 benzoyl chloride 
• 582-25-2 Potassium benzoate 
• 614-28-8 N-benzoylbenzamide 

Downstream Products

• 94618-80-1 N-oxy methyl-imino-17 benzoyl-3β androstene-4 
• 154229-18-2 abiraterone acetate 
• 154229-19-3 abiraterone 
• 1470067-73-2 16-Formyl-17-chloroandrost-5,16-diene-3β-yl benzoate 
• 1470067-91-4 16-formyl-17-(1H-pyrazole-1-yl)androsta-5,16-diene-3β-yl benzoate 
• 102218-12-2 17β-Hydroxycarbamoyloxy-3β-benzoyloxy-androsten-(5) 
• 103070-90-2 17β-Chlorformyloxy-3β-benzoyloxy-androsten-(5) 
• 901-62-2 7α-Methoxy-Δ⁵-androsten-ol-(3β)-on-(17) 
• 851-24-1 7β-Methoxy-3β-hydroxy-17-oxo-androsten-5 
• 135637-63-7 3β-hydroxy-4aα-methyl-A-homo-B,19-dinor-5β,10α-androstan-17-one 3-cyclohexanecarboxylate 
• 135574-00-4 3β-hydroxy-4aα-methyl-A-homo-B,19-dinor-5α,9β-androstan-17-one 3-cyclohexanecarboxylate 
• 135573-98-7 17,17-ethylenedioxy-5-methyl-19-nor-5β-androst-9-ene-3β,6β-diol 3-benzoate 6-methanesulfonate 
• 135573-96-5 3β,6β-dihydroxy-5-methyl-19-nor-5β-androst-9-en-17-one 3-benzoate 6-methanesulfonate 
• 135573-94-3 3β,6β-dihydroxy-5-methyl-19-nor-5β-androst-9-en-17-one 3-benzoate 6-acetate 

Relevant articles and documents

Method for preparing abiraterone acetate

The invention provides a method for preparing abiraterone acetate. Specifically, the invention relates to an improved method for synthesizing abiraterone or a derivative thereof through a key 3 beta-benzoyloxy intermediate. According to the process, intermediate DHEA 3-benzoyloxy ester is a solid, the intermediate with higher purity can be obtained through a crystallization method, and the processoperability is high. Meanwhile, benzoyl is strong in electric negative force, easy to react with hydroxyl and high in acylation rate, and a six-membered ring structure is twisted in a space structureof a benzoyl functional group, so that elimination reaction is not easy to perform, and generation of process byproducts is effectively avoided.

Cytotoxic effect of novel dehydroepiandrosterone derivatives on different cancer cell lines

The aim of this study was to determine the cytotoxic effect of human cancer cells on three series of novel dehydroepiandrosterone derivatives containing triazole or pyrazole rings at C-17 and an ester moiety at C-3 of the androstane skeleton. The panel ca

Synthesis and Antitumor Activity of Dehydroepiandrosterone Derivatives on Es-2, A549, and HepG2 Cells in vitro

A series of dehydroepiandrosterone derivatives containing an acid ester was synthesized and evaluated for their antitumor activity on ES-2, A549, and HepG2 cells by the MTT assay. Most compounds showed antitumor activity, while compounds 1c, 2i, and 2o exhibited more potential inhibitory effects compared with dehydroepiandrosterone on ES-2 cells, A549 cells, and HepG2 cells, respectively.