14717-30-7Relevant articles and documents
P-Chiral Monophosphorus Ligands for Asymmetric Copper-Catalyzed Allylic Alkylation
Xiong, Wenrui,Xu, Guangqing,Yu, Xinhong,Tang, Wenjun
, p. 4003 - 4013 (2019/06/24)
Asymmetric copper-catalyzed allylic alkylation between allyl bromides and alkyl Grignard reagents using a P-chiral monophosphorus ligand is described. A range of terminal olefins bearing tertiary or quaternary carbon centers were formed in good branched/linear selectivities and excellent enantioselectivities at copper loadings as low as 0.5 mol %.
Highly regioselective asymmetric copper-catalyzed allylic alkylation with dialkylzincs using monodentate chiral spiro phosphoramidite and phosphite ligands
Shi, Wen-Jian,Wang, Li-Xin,Fu, Yu,Zhu, Shou-Fei,Zhou, Qi-Lin
, p. 3867 - 3872 (2007/10/03)
The copper complexes of chiral spiro phosphoramidite and phosphite ligands were found to be effective catalysts in the asymmetric allylic alkylations of cinnamyl halides with dialkylzincs. The allylic alkylation products were obtained in high regioselecti
The synthesis of carboxylic acids via an aldol-grob reaction sequence
Kabalka,Li,Tejedor,Malladi,Gao,Trotman
, p. 2783 - 2787 (2007/10/03)
Ketones react with aromatic aldehydes via a tandem Aldol-Grob reaction sequence. The reaction, initiated by boron trifluoride, produces a carboxylic acid fragment and can serve as an alternative to the Baeyer-Villiger reaction.