147356-80-7Relevant articles and documents
Biscyclopropyl titanocene: A novel reagent for the synthesis of alkylidene and vinyl cyclopropanes
Petasis, Nicos A.,Bzowej, Eugene I.
, p. 943 - 946 (1993)
Alkylidene cyclopropane derivatives are obtained by reaction of biscyclopropyl titanocene with several types of carbonyl compounds, including aldehydes, ketones and esters. In some cases the isomeric vinyl cyclopropane products are also obtained. Biscyclopropyl titanocene also reacts with alkynes forming, after acidification, the corresponding vinyl cyclopropanes.
Synthesis of Fluorinated Homoallylic Compounds by Fluoroalkyl Radical Mediated Ring Opening of Methylenecyclopropanes
Xie, Huajun,Xu, Bo
supporting information, p. 2594 - 2598 (2016/06/08)
The fluoroalkyl (Rf) radical mediated ring opening of methylenecyclopropanes (MCPs) 1 and subsequent atom transfer were investigated. In the first part, a copper-initiated radical reaction of Rf-X (X = I, Br) with MCP 1 gave homoallylic halides 2 in excellent yields. Similarly, radical reaction of the RfTMS/CsF/PhI(OCOR)2 system with MCP 1 led to homoallylic alcohol esters 3 in moderate to good yields. An efficient synthesis of fluoroalkyl (Rf)-substituted homoallylic halides 2 and homoallylic alcohol esters 3 by fluoroalkyl radical mediated ring opening of methylenecyclopropanes (MCPs) 1 followed by an atom-transfer process is developed.