1474019-91-4

Basic information

• Product Name: (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate
• Synonyms: (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate
• CAS NO: 1474019-91-4
• Molecular Weight: 798.89
• Mol File: 1474019-91-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate(1474019-91-4)
• EPA Substance Registry System: (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate(1474019-91-4)

Safety Data

• Hazardous Substances Data: 1474019-91-4(Hazardous Substances Data)

Upstream product

• 159847-81-1 methyl 2-AMINO-5-CYANOBENZOATE 
• 1246999-33-6 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate) 
• 106984-09-2 2-<2-<2-<2-<(tert-Butoxycarbonyl)amino>ethoxy>ethoxy>ethoxy>ethanol 
• 86770-74-3 11-amino-3,6,9-trioxaundecanol 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1246999-34-7 tert-butyl (2-(2-(2-(2-(3-hydroxyphenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate 
• 1474019-88-9 methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-aminobenzoate 

Downstream Products

• 1474019-94-7 (E)-methyl 5-(aminomethyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate 
• 1474019-95-8 (E)-5-(aminomethyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoic acid 
• 1474019-97-0 (E)-5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoic acid 
• 1474020-00-2 (E)-5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)-4-hydroxyphenyl)diazenyl)benzoic acid trifluoroacetic salt 
• 1474020-03-5 5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((E)-(4-hydroxy-2-((13-oxo-17-((4S)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecyl)oxy)phenyl)diazenyl)benzoic acid 

Relevant articles and documents

Bioorthogonal approach to identify unsuspected drug targets in live cells

A proteomics method to pull down secondary drug targets from live cells is described. The drug of interest is modified with trans-cyclooctene (TCO) and incubated with live cells. Upon cell lysis, the modified drug bound to the protein is pulled down using magnetic beads decorated with a cleavable tetrazine-modified linker. Samples are then run on an SDS-PAGE gel and isolated bands are submitted for mass spectrometry analysis to identify drug targets. Copyright