1246999-33-6

Basic information

• Product Name: 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)
• Synonyms: 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)
• CAS NO: 1246999-33-6
• Molecular Weight: 447.55
• Mol File: 1246999-33-6.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)(1246999-33-6)
• EPA Substance Registry System: 2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)(1246999-33-6)

Safety Data

• Hazardous Substances Data: 1246999-33-6(Hazardous Substances Data)

Usage

General Description

The chemical "2-(2-(2-(2-((tert-butoxycarbonyl)amino)ethoxy)ethoxy)ethoxy)ethyl-(4'-methylbenzolsulfonate)" is a compound derived from the combination of several chemical groups. It contains a tert-butoxycarbonyl (Boc) protecting group, which is often used in organic synthesis to protect amine groups. Additionally, it consists of a benzene sulfonate group, which is commonly used as a leaving group in organic reactions. Overall, the compound is a complex molecule with multiple functional groups, and it is likely used in organic chemistry research and synthesis processes.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 168640-82-2 11-azido-3,6,9-trioxa-undecanyl p-toluenesulfonate 
• 37860-51-8 tetraethylene glycol di(p-toluenesulfonate) 
• 112-60-7 Tetraethylene glycol 
• 98-59-9 p-toluenesulfonyl chloride 
• 106984-09-2 2-<2-<2-<2-<(tert-Butoxycarbonyl)amino>ethoxy>ethoxy>ethoxy>ethanol 
• 86770-74-3 11-amino-3,6,9-trioxaundecanol 
• 34619-03-9 tert-butyldicarbonate 
• 147912-26-3 2-(2-(2-(2-t-butoxyethoxy)ethoxy)ethoxy)ethanol 
• 86770-67-4 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethanol 
• 77544-60-6 p-toluenesulfonic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester 

Downstream Products

• 1310568-65-0 C₃₇H₇₀NO₁₇P 
• 1310568-66-1 C₆₄H₁₀₀N₃O₂₂PS₂ 
• 1310568-67-2 C₆₀H₉₂N₃O₂₂PS₂ 
• 1310568-64-9 C₄₂H₇₈NO₁₉P 
• 1474019-91-4 (E)-methyl 5-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate 
• 1474019-94-7 (E)-methyl 5-(aminomethyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoate 
• 1474019-95-8 (E)-5-(aminomethyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoic acid 
• 1474019-97-0 (E)-5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((2-((2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yl)oxy)-4-hydroxyphenyl)diazenyl)benzoic acid 
• 1474020-00-2 (E)-5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)-4-hydroxyphenyl)diazenyl)benzoic acid trifluoroacetic salt 
• 1474020-03-5 5-((5-((4-(1,2,4,5-tetrazin-3-yl)benzyl)amino)-5-oxopentanamido)methyl)-2-((E)-(4-hydroxy-2-((13-oxo-17-((4S)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecyl)oxy)phenyl)diazenyl)benzoic acid 
• 1246999-34-7 tert-butyl (2-(2-(2-(2-(3-hydroxyphenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate 

Relevant articles and documents

Pyrene-Based “Turn-Off” Probe with Broad Detection Range for Cu2+, Pb2+ and Hg2+ Ions

Detection of metals in different environments with high selectivity and specificity is one of the prerequisites of the fight against environmental pollution with these elements. Pyrenes are well suited for the fluorescence sensing in different media. The

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-CONTAINING PROTEINS

The present invention relates to bifunctional compounds, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present invention. In particular, the present invention is directed to compounds, which contain on one end a VHL ligand which binds to the ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. The present invention exhibits a broad range of pharmacological activities associated with compounds according to the present invention, consistent with the degradation/inhibition of targeted polypeptides.