147510-56-3

Basic information

• Product Name: Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester
• Synonyms: Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester
• CAS NO: 147510-56-3
• Molecular Weight: 458.919
• Mol File: 147510-56-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester(147510-56-3)
• EPA Substance Registry System: Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester(147510-56-3)

Safety Data

• Hazardous Substances Data: 147510-56-3(Hazardous Substances Data)

Upstream product

• 34487-61-1 phenolsulphophthaleine sodium salt 
• 172464-36-7 2-(4,4'-dihydroxy-benzhydryl)-benzenesulfonic acid 
• 115481-75-9 pyridinium 2-benzenesulfonate 

Downstream Products

• 115481-73-7 Bis(phenol) phenyl sulfonate 
• 115511-92-7 bis(4.acetoxyphenyl)<2-(phenoxysulfonyl)phenyl>methane 

Relevant articles and documents

Bis(4-hydroxyphenyl)methane: Isolation and Structure Elucidation of a Novel Estrogen from Commercial Preparations of Phenol Red (Phenolsulfonphthalein)

Commercial preparations of phenolsulfonphthalein (Phenol Red), a pH indicator dye widely added to cell culture media, have weak estrogenic activity that can be accounted for by a minor lipophilic impurity (ca. 0.002percent).We have isolated this impurity, determined its structure to be bis(4-hydroxyphenyl)methane, and synthesized it from phenolsulfonphthalein.This compound binds to the estrogen receptor with an affinity 50percent that of estradiol; it stimulates the proliferation and increases the progesterone receptor content of estrogen-responsive breast cancer cells in vitro, and stimulates uterine weight gain in rats in vivo, but shows a potency in these assays only 0.1-0.2percent that of estradiol.We suggest haw this novel estrogen may be generated during the preparation of phenolsulfonphthalein.