148416-38-0

Basic information

• Product Name: 2,3,4-Trifluoro-6-nitroaniline
• Synonyms: 6-NITRO-2,3,4-TRIFLUOROANILINE;2-NITRO-4,5,6-TRIFLUOROANILINE;2,3,4-TRIFLUORO-6-NITROANILINE;BUTTPARK 24\01-62;6-Nitro-2,3,4-trifluoroaniline 97%;6-Nitro-2,3,4-trifluoroaniline97%;2,3,4-TRIFLUORO-6-NITROANILINE 99%;2,3,4-Trifluoro-6-ni
• CAS NO: 148416-38-0
• Molecular Formula: C₆H₃F₃N₂O₂
• Molecular Weight: 192.1
• Product Categories: Amines;C2 to C6;Nitrogen Compounds
• Mol File: 148416-38-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 59-61 °C(lit.)
• Boiling Point: 287.6 °C at 760 mmHg
• Flash Point: 127.7 °C
• Appearance: White/Powder
• Density: 1.653 g/cm³
• Vapor Pressure: 0.27mmHg at 25°C
• Refractive Index: 1.451
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: soluble in Methanol
• PKA: -2.75±0.25(Predicted)
• CAS DataBase Reference: 2,3,4-Trifluoro-6-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-Trifluoro-6-nitroaniline(148416-38-0)
• EPA Substance Registry System: 2,3,4-Trifluoro-6-nitroaniline(148416-38-0)

Safety Data

• Hazard Codes: Xi,T,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• WGK Germany: 3
• HazardClass: TOXIC
• Hazardous Substances Data: 148416-38-0(Hazardous Substances Data)

Usage

Chemical Properties

White to yellow solid

InChI:InChI=1/C9H7F3O3/c1-14-8(13)6-4-2-3-5-7(6)15-9(10,11)12/h2-5H,1H3

Upstream product

• 365-29-7 N-(2,3,4-trifluorophenyl)acetamide 
• 3862-73-5 2,3,4-trifluoroaniline 
• 290313-50-7 6-nitro-2,3,4-trifluoroacetanilide 
• 5580-79-0 2,3,4,5-tetrafluoro-1-nitrobenzene 

Downstream Products

• 168966-54-9 3,4,5-Trifluoro-1,2-phenylenediamine 
• 587847-30-1 4,5,6-trifluoro-2-nitrophenylazide 
• 906081-32-1 3-amino-2,6-difluoro-4-nitro-phenol 
• 906081-33-2 3,4-diamino-2,6-difluoro-phenol 
• 66684-58-0 3,4,5-trifluoronitrobenzene 
• 934765-48-7 4-[(3-amino-2,6-difluoro-4-nitrophenyl)oxy]benzaldehyde 
• 1477492-17-3 2,6-difluoro-N₁-(4-fluorobenzyl)-4-nitrobenzene-1,3-diamine 
• 1477492-04-8 ethyl (2-amino-3,5-difluoro-4-((4-fluorobenzyl)amino)phenyl)carbamate 
• 1196131-58-4 5,6,7-triifluoro-2-phenyl-1H-benzimidazole 

Relevant articles and documents

Fluorinated 2-Amino-4-(Benzylamino)Phenylcarbamate Derivatives

The invention relates to fluorinated compounds and their use as anti-epileptic, muscle-relaxing, fever-reducing and peripherally analgesically acting medications and as imaging agents. Novel fluorinated 2-amino-4-(benzylamino)phenyl carbamate derivatives of ezogabine and pharmaceutically acceptable salts or solvates thereof and their use are described.

Synthesis of novel fluorobenzofuroxans by oxidation of anilines and thermal cyclization of arylazides

The synthesis of several fluorobenzofuroxans by oxidation of fluoroanilines and thermal cyclization of fluoroarylazides is presented. The fluorobenzofuroxans prepared in this study presented tautomerism as evidenced by their NMR data. Benzofuroxans in general have biological activity and are synthetic intermediates for the preparation of several compounds with important pharmaceutical applications.