14850-89-6Relevant articles and documents
Analogs of Nitrofuran Antibiotics to Combat Resistance
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Paragraph 0125; 0162; 0194; 0196, (2022/01/24)
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Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs
Chapman, Eli,Chitre, Siddhi,Hoang, Quyen Q.,Howe, Chris,Johnson, Steven M.,Park, Yangshin,Ray, Anne-Marie,Sivinski, Jared,Stevens, Mckayla,Washburn, Alex
, (2020/09/15)
In two previous studies, we identified compound 1 as a moderate GroEL/ES inhibitor with weak to moderate antibacterial activity against Gram-positive and Gram-negative bacteria including Bacillus subtilis, methicillin-resistant Staphylococcus aureus, Kleb
Sodium hypochlorite-mediated synthesis of 2,5-disubstituted 1,3,4-oxadiazoles from hydrazides and aldehydes
Paidi, Karuna Raman,Kolli, Murali Krishna,Reddy, Eeda Koti,Pedakotla, Venkata Ramana
, p. 371 - 376 (2020/05/04)
[Figure not available: see fulltext.] A simple and convenient method for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles has been developed. Structurally divergent symmetrical and unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles can be obtained in moderate to high yields via NaOCl-mediated oxidative cyclization of N-acylhydrazones, generated in situ from aliphatic and aromatic hydrazides and aldehydes.