148928-15-8 Usage
Description
FMOC-ISONIPECOTIC ACID, also known as 9-fluorenylmethoxycarbonyl-isonipecotic acid, is a chemical compound that serves as a valuable building block in the synthesis of various peptides and pharmaceuticals. It is a white powder with unique chemical properties that make it suitable for use in the development of anti-thrombotic agents.
Uses
Used in Pharmaceutical Industry:
FMOC-ISONIPECOTIC ACID is used as a building block for the synthesis of anti-thrombotic peptide libraries. Its incorporation into peptide structures aids in the development of novel therapeutic agents that can help prevent blood clot formation, which is a critical factor in the treatment and management of various cardiovascular diseases.
Additionally, FMOC-ISONIPECOTIC ACID can be utilized in other applications within the pharmaceutical industry, such as the synthesis of other bioactive peptides or as a component in drug delivery systems, due to its versatile chemical properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 148928-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,2 and 8 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 148928-15:
(8*1)+(7*4)+(6*8)+(5*9)+(4*2)+(3*8)+(2*1)+(1*5)=168
168 % 10 = 8
So 148928-15-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H21NO4/c23-20(24)14-9-11-22(12-10-14)21(25)26-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,14,19H,9-13H2,(H,23,24)
148928-15-8Relevant articles and documents
Radical-Mediated Activation of Esters with a Copper/Selectfluor System: Synthesis of Bulky Amides and Peptides
Matsumoto, Akira,Wang, Zhe,Maruoka, Keiji
, p. 5401 - 5411 (2021/04/12)
Herein, we describe a new approach for the activation of esters via a radical-mediated process enabled by a copper/Selectfluor system. A variety of para-methoxybenzyl esters derived from bulky carboxylic acids and amino acids can be easily converted into the corresponding acyl fluorides, directly used in the one-pot synthesis of amides and peptides. As a proof of concept, this method was applied to the iterative formation of sterically hindered amide bonds.
IMIDAZOTRIAZINONE COMPOUNDS
-
Paragraph 0551; 0552, (2013/10/08)
The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9 and pharmaceutically acceptable salt thereof. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.
Diaminopropionic acid derivatives
-
, (2008/06/13)
A compound of formula 1a which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.