149489-03-2

Basic information

• Product Name: CARBAMIC ACID, (3-ETHYL-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER
• Synonyms: 2-t-ButoxycarbonylaMino-3-ethylpyridine;(3-Ethyl-pyridin-2-yl)-carbamic acid tert-butyl ester;CARBAMIC ACID, (3-ETHYL-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER;N-(3-Ethyl-2-pyridinyl)carbamic acid tert-butyl ester;N-Boc-3-ethylpyridin-2-amine;Carbamic acid,(3-ethyl-2-pyridinyl)-,1,1-dimethylethyl ester (9Cl);tert-butyl 3-ethylpyridin-2-ylcarbamate;EOS-61815
• CAS NO: 149489-03-2
• Molecular Formula: C12H18N2O2
• Molecular Weight: 222.286
• Mol File: 149489-03-2.mol
• Article Data: 6

Chemical Properties

• Appearance: White to off-white powder
• Density: 1.087
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CARBAMIC ACID, (3-ETHYL-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAMIC ACID, (3-ETHYL-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(149489-03-2)
• EPA Substance Registry System: CARBAMIC ACID, (3-ETHYL-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER(149489-03-2)

Safety Data

• Hazardous Substances Data: 149489-03-2(Hazardous Substances Data)

Usage

General Description

Carbamic acid, (3-ethyl-2-pyridinyl)-, 1,1-dimethylethyl ester is a chemical compound whose specific structure includes the carbamate ester functional group. It's notable for its inclusion of a 3-ethyl-2-pyridinyl component, which belongs to the class of organic compounds known as pyridines and derivatives. These are compounds containing a pyridine ring, which is a six-membered aromatic heterocycle, with a nitrogen atom at one position, and a 3-ethyl-2-pyridinyl moiety. Additionally, the 1,1-dimethylethyl ester moiety in its structure suggests that it could participate in esterification reactions. However, detailed information about its specific properties, uses, or potential hazards is not readily available, indicating that it’s likely a specialized or less-commonly encountered substance.

Upstream product

• 138343-75-6 tert-butyl (3-methylpyridin-2-yl)carbamate 
• 74-88-4 methyl iodide 
• 1603-40-3 3-methylpyridin-2-ylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 109-72-8 n-butyllithium 
• 38427-94-0 N-(tert-butoxycarbonyl)-2-aminopyridine 
• 75-03-6 ethyl iodide 

Downstream Products

• 5654-93-3 3-methyl-1H-pyrrolo<2,3-b>pyridine 
• 10299-69-1 2,3-dimethyl-1H-pyrrolo[2,3-b]pyridine 
• 139962-70-2 2-phenyl-3-methyl-1H-pyrrolo[2,3-b]pyridine 
• 42753-67-3 2-amino-3-ethylpyridine 
• 1037253-14-7 5-bromo-3-ethylpyridin-2-amine 

Relevant articles and documents

PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORyT

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, Ra, Rb, Q1, and Q2 are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-γ-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

AZABICYCLO COMPOUND AND SALT THEREOF

It is intended to provide a novel azabicyclo compound which exhibits both HSP90 inhibitory activity and cell proliferation inhibitory effect. Specifically disclosed is a compound represented by the following general formula (I) or a salt thereof: wherein X1 represents CH or N; any one of X2, X3 and X4 represents N, and the others represent CH; any one or two of Y1, Y2, Y3 and Y4 represent C—R4, and the others are the same or different and represent CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S and O; R2 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R3 and R4 represent —CO—R5 or the like.

Method for inhibition of HIV related viruses

Treatment of AIDS, inhibition of the replication of HIV and related viruses thereof, and formulations using thiourea derivative compounds or salts thereof is disclosed. Also disclosed are novel thiourea derivative compounds.