15015-46-0Relevant articles and documents
Regioselective Organocatalytic Formation of Carbamates from Substituted Cyclic Carbonates
Sope?a, Sergio,Laserna, Victor,Guo, Wusheng,Martin, Eddy,Escudero-Adán, Eduardo C.,Kleij, Arjan W.
supporting information, p. 2172 - 2178 (2016/07/16)
A highly regioselective catalytic approach has been developed towards carbamates derived from cyclic organic carbonates by reaction of the latter with amine reagents under organocatalytic control. For various combinations of carbonate and amine substrates, an organocatalyst (TBD: 1,5,7-triazabicyclo[4.4.0]dec-5-ene) was used to increase the reaction kinetics while exerting excellent regioselective control. The current method is the first general approach towards the control over the regioselectivity of this reaction using a wide variety of easily accessed substituted organic carbonates. (Figure presented.) .
Retropinacol/cross-pinacol coupling reactions - A catalytic access to 1,2-unsymmetrical diols
Scheffler, Ulf,Stoesser, Reinhard,Mahrwald, Rainer
supporting information, p. 2648 - 2652,5 (2012/12/12)
A new concept to access unsymmetrical 1,2-diols with high yields is reported. This new methodology is based on a retropinacol/cross-pinacol coupling process. This transformation is characterized by its operational simplicity and very mild reaction condi tions.
C,O-dilithiated diarylmethanols: Easy and improved preparation by naphthalene-catalysed lithiation of diaryl ketones and reactivity toward electrophiles
Guijarro,Mancheno,Yus
, p. 1327 - 1334 (2007/10/02)
The lithiation of different diaryl ketones 1 with an excess of lithium powder and a catalytic amount (8 mol %) of naphthalene in tetradrofuran at -30°C leads to the formation of the corresponding dianions of the type I, with Met=Li, which react with several electrophiles (E+=MeI, EtBr, Pr(i)CHO, PhCHO, cyclohexanone, MeCN) to give, after hydrolysis, the expected substituted diarylmethanols 2.