15085-20-8 Usage
Description
2,3-Dihydro-7-methyl-1H-indene-4-carbonitrile, also known as 4-Cyano-7-methylindan, is an organic compound with the chemical formula C11H9N and a CAS number of 15085-20-8. It is an off-white to pale yellow solid and is primarily used in organic synthesis due to its unique chemical structure and properties.
Uses
Used in Organic Synthesis:
2,3-Dihydro-7-methyl-1H-indene-4-carbonitrile is used as a synthetic building block for the creation of various organic compounds. Its application in organic synthesis is due to its ability to undergo a range of chemical reactions, such as substitution, addition, and condensation, which can lead to the formation of a diverse array of molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3-Dihydro-7-methyl-1H-indene-4-carbonitrile is used as an intermediate in the synthesis of various drugs and drug candidates. Its unique structure allows for the development of new molecules with potential therapeutic properties, making it a valuable compound in the search for novel pharmaceutical agents.
Used in Chemical Research:
2,3-Dihydro-7-methyl-1H-indene-4-carbonitrile is also used in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and structural features make it an ideal candidate for exploring new chemical reactions and understanding the underlying principles governing these processes.
Used in Material Science:
In the field of material science, 2,3-Dihydro-7-methyl-1H-indene-4-carbonitrile can be used as a precursor to develop novel materials with specific properties, such as improved stability, enhanced conductivity, or unique optical characteristics. Its versatility in organic synthesis allows for the creation of new materials with potential applications in various industries, including electronics, energy, and aerospace.
Check Digit Verification of cas no
The CAS Registry Mumber 15085-20-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,8 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15085-20:
(7*1)+(6*5)+(5*0)+(4*8)+(3*5)+(2*2)+(1*0)=88
88 % 10 = 8
So 15085-20-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N/c1-8-5-6-9(7-12)11-4-2-3-10(8)11/h5-6H,2-4H2,1H3
15085-20-8Relevant articles and documents
Improved Synthesis of 3-Methylcholanthrene
Tang, Ping Wah,Maggiulli, Cataldo A.
, p. 3429 - 3432 (2007/10/02)
An improved synthesis of 7-methylindan-4-yl 1-naphthyl ketone (3), an important precursor of 3-methylcholanthrene (1), has been developed.The key intermediates for 3, 4-cyano-7-methylindan (2a) and 4-(ethoxycarbonyl)-7-methylindan (2b), were conveniently prepared in high yields by reaction of 1-(1-pyrrolidino)cyclopentene (6) with sorbonitrile (5a) or ethyl sorbate (5b), followed by aromatization with sulfur. 1-Naphthylmagnesium bromide (4b) in the presence of cuprous iodide reacted cleanly with 4-(chloromethanoyl)-7-methylindan (12) to give 3.The Friedel-Crafts acylation of naphthalene with 12 afforded 84percent of 3 and 16percent of β isomer 13.Alternatively, 3 was prepared in 75percent yield by condensation of Grignard reagent 4b with 2a in THF.Thermal annelation of 3 afforded 1 in 41.5percent yield.
