1510-24-3

Basic information

• Product Name: 4-Isothiocyanato-1,1'-biphenyl
• Synonyms: 4-Isothiocyanato-1,1'-biphenyl;4-Isothiocyanatobiphenyl;Biphenyl-4-yl isothiocyanate;p-Xenyl mustard oil;1-isothiocyanato-4-phenylbenzene
• CAS NO: 1510-24-3
• Molecular Formula: C₁₃H₉NS
• Molecular Weight: 211.28
• Mol File: 1510-24-3.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 357.6°Cat760mmHg
• Flash Point: 180°C
• Appearance: /
• Density: 1.06g/cm³
• CAS DataBase Reference: 4-Isothiocyanato-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isothiocyanato-1,1'-biphenyl(1510-24-3)
• EPA Substance Registry System: 4-Isothiocyanato-1,1'-biphenyl(1510-24-3)

Safety Data

• Hazardous Substances Data: 1510-24-3(Hazardous Substances Data)

Upstream product

• 19250-03-4 biphenyl-4-yl-thiourea 
• 92-96-6 N,N'-bis-biphenyl-4-yl-thiourea 
• 463-71-8 thiophosgene 
• 92-67-1 4-phenylalanine 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 1430796-58-9 C₁₃H₁₁NS₂*C₆H₁₂N₂ 
• 106-40-1 4-bromo-aniline 
• 98-80-6 phenylboronic acid 
• 540-37-4 p-aminoiodobenzene 
• 75-15-0 carbon disulfide 
• 421-83-0 trifluoromethane sulfonyl chloride 

Downstream Products

• 851904-80-8 1-(biphenyl-4-yl)-3-propylthiourea 
• 92-96-6 N,N'-bis-biphenyl-4-yl-thiourea 
• 101894-73-9 N-biphenyl-4-yl-N'-(4-chloro-phenyl)-thiourea 
• 4474-04-8 N-(1,1'-biphenyl-4-yl)-N'-phenylthiourea 
• 102318-20-7 N-(4-ethoxy-phenyl)-N'-biphenyl-4-yl-thiourea 
• 101937-36-4 N-biphenyl-4-yl-N'-(4-bromo-phenyl)-thiourea 
• 927407-23-6 C₁₉H₁₇N₃S 
• 883557-29-7 biphenyl-4-yl-[5-(2-methyl-pyridin-3-yl)-[1,3,4]oxadiazol-2-yl]-amine 

Relevant articles and documents

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Synthesis of N-CF3Alkynamides and Derivatives Enabled by Ni-Catalyzed Alkynylation of N-CF3Carbamoyl Fluorides

The expansion of chemical space associated with ubiquitous motifs is key to unleash new properties and functions. In this context, alkynamides, prevalent in numerous drugs and materials, represent an untapped resource. We herein report the first synthetic access to N-trifluoromethyl alkynamides. Our strategy relies on a mild and operationally simple Ni-catalyzed coupling of N-CF3 carbamoyl fluorides with alkynyl silanes. The synthesized N-CF3 alkynamides proved to be highly robust and readily functioned as a platform to unlock access to valuable derivatives, such as N-CF3 decorated alkenyl amides, oxindoles, or quinolones, all of which were inaccessible to date.

Synthesis of thiocarbamoyl fluorides and isothiocyanates using amines with CF3SO2Cl

A practical and efficient method to synthesize thiocarbamyl fluorides and isothiocyanates from amines with trifluoromethanesulfonyl chloride was developed. In the presence of the reducing agent triphenylphosphine and sodium iodide, thiocarbamyl fluorides and isothiocyanates were synthesized from secondary/primary amine in moderate to excellent yields, respectively. A broad scope of substrates and good functional group compatibility were observed.