151133-39-0

Basic information

• Product Name: 1,2,5-Thiadiazole, 3-bromo-4-phenyl-
• CAS NO: 151133-39-0
• Molecular Formula: C8H5BrN2S
• Molecular Weight: 241.111
• Mol File: 151133-39-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2,5-Thiadiazole, 3-bromo-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Thiadiazole, 3-bromo-4-phenyl-(151133-39-0)
• EPA Substance Registry System: 1,2,5-Thiadiazole, 3-bromo-4-phenyl-(151133-39-0)

Safety Data

• Hazardous Substances Data: 151133-39-0(Hazardous Substances Data)

Upstream product

• 5728-12-1 4-phenyl-[1,2,5]thiadiazol-3-ol 
• 14181-72-7 2-bromo-1-phenyl-ethanone oxime 

Downstream Products

• 69643-34-1 3-(4-chloro-phenyl)-4-phenyl-[1,2,5]thiadiazole 

Relevant articles and documents

Reactions of 1-aryl-2,2-dihalogenoethanone oximes with tetrasulfur tetranitride (S4N4): A general method for the synthesis of 3-aryl-4-halogeno-1,2,5-thiadiazoles

1-Aryl-2,2-dichloro-7, 1-aryl-2,2-dibromo-8, 1-aryl-2-bromo-2-fluoro-9 and 1-aryl-2-chloro-2-fluoroethanone oximes 10 have been prepared by allowing the corresponding ketones to react with hydroxylamine hydrochloride in EtOH at room temperature. Stereoche

Reactions of Monohalomethyl Aryl Ketoximes with Tetrasulfur Tetranitride: Much Improved Synthesis of 3-Aryl-1,2,5-thiadiazoles

Reactions of chloromethyl aryl ketoximes (1, X = Cl) with tetrasulfur tetranitride in p-dioxane at reflux for 4 h afforded 3-aryl-1,2,5-thiadiazoles (2) in 37-92percent yields, whereas those of bromo analogs under the same conditions gave 2 and 3-aryl-4-bromo-1,2,5-thiadiazoles 3 in 48-81percent and 17-31percent yields, respectively.However, the compounds (3) were not formed in the presence of pyridine. α-Nitrosostyrene and its ring-substituted derivatives (4) are proposed as intermediates for the formations of 2.