1516887-33-4 Usage
Description
(E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid is a complex organic compound with a unique molecular structure. It is characterized by the presence of a hydroxyl group at the 3α position, an ethylidene group at the 6 position, a ketone group at the 7 position, and a carboxylic acid group at the 24 position. (E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid is derived from the cholestane skeleton, which is a common structural framework for many steroids.
Uses
Used in Pharmaceutical Industry:
(E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid is used as a byproduct in the synthesis of Obeticholic Acid (E899810) for its potential application in the treatment of liver diseases. Its unique structure and functional groups make it a valuable intermediate in the development of pharmaceutical compounds targeting liver conditions.
Used in Liver Disease Treatment:
(E)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid may be useful in the treatment of liver diseases due to its structural similarity to bile acids, which play a crucial role in the digestion and absorption of dietary fats. Its potential application in this area could provide new therapeutic options for patients suffering from various liver conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1516887-33-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,1,6,8,8 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1516887-33:
(9*1)+(8*5)+(7*1)+(6*6)+(5*8)+(4*8)+(3*7)+(2*3)+(1*3)=194
194 % 10 = 4
So 1516887-33-4 is a valid CAS Registry Number.
1516887-33-4Relevant articles and documents
(E)-3 alpha-hydroxy-6-ethylidene-7-oxo-5 beta-cholestane-24-acid preparation method
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, (2020/01/25)
The invention discloses a (E)-3 alpha-hydroxy-6-ethylidene-7-oxo-5 beta-cholestane-24-acidpreparation method, which specially comprises: 1, carrying out a condensation reaction on 3 alpha-hydroxy-7-oxo-5 beta-cholestane-24-acid methyl ester to obtain 3 al
Preparing method of (E)-3alpha-hydroxy-6-ethidene-7-keto-5beta-cholane-24-acid
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, (2017/11/01)
The invention discloses a preparing method of (E)-3alpha-hydroxy-6-ethidene-7-keto-5beta-cholane-24-acid. Particularly, the preparing method includes the following steps of synchronously protecting of the 3-alcoholic hydroxyl group and the 7-enolic hydroxyl group; introducing a 6-carbon-carbon double bond and removing a protecting group; hydrolyzing an ester intermediate and recrystallizing the final product. Compared with a method for preparing (E)-3alpha-hydroxy-6-ethidene-7-keto-5beta-cholane-24-acid in the prior art, the preparing method has the advantages of being stable in reaction, high in yield, small in amount of side reaction, high in quality and the like and has broad development and application prospects.
