3360-89-2 Usage
Description
(5β,6α)-6-Hydroxy-3-oxo-cholan-24-oic Acid Methyl Ester is a 6α-hydroxy bile acid analog, which is a type of steroid molecule derived from the modification of naturally occurring bile acids. It is characterized by its dark oil appearance and possesses unique chemical properties that make it suitable for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
(5β,6α)-6-Hydroxy-3-oxo-cholan-24-oic Acid Methyl Ester is used as an intermediate compound in the synthesis of important pharmaceutical products, such as progesterone (P755900) and α-Hyodeoxycholic Acid (H998100). These compounds have significant applications in the treatment of various medical conditions and hormonal imbalances.
Used in Chemical Industry:
(5β,6α)-6-Hydroxy-3-oxo-cholan-24-oic Acid Methyl Ester is also utilized as a key building block in the chemical industry for the development of novel steroidal compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 3360-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,6 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3360-89:
(6*3)+(5*3)+(4*6)+(3*0)+(2*8)+(1*9)=82
82 % 10 = 2
So 3360-89-2 is a valid CAS Registry Number.
3360-89-2Relevant articles and documents
Analysis of conjugated bile acids in human biological fluids. Synthesis of hyodeoxycholic acid 3- and 6-glycosides and related compounds
Iida,Tazawa,Ohshima,Niwa,Goto,Nambara
, p. 1479 - 1484 (1994)
The glucuronide, glucoside and N-acetylglucosaminide conjugates of hyodeoxycholic acid were synthesized. In addition, murideoxycholic acid 3- glycosides and some of their C-5 epimeric analogs were also prepared. The principal reactions used are 1) the Koenigs-Knorr condensation reaction of 3- oxo-6α-hydroxy and 6-oxo-3α-hydroxy esters with an appropriate α- acetohalosugar catalyzed by cadmium carbonate in benzene under reflux, 2) reduction of the resulting bile acid glycoside methyl ester-acetates with tert-butylamine-borane complex, and 3) subsequent hydrolysis with aqueous lithium hydroxide.
METHOD FOR PREPARING A FARNESOID X RECEPTOR AGONIST
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Page/Page column 24; 25, (2017/11/04)
The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.
NEW STEROID INHIBITORS OF PGP FOR USE FOR INHIBITING MULTIDRUG RESISTANCE
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Page/Page column 73-74, (2011/07/07)
The present invention relates to a compound of formula (I) for its use for reversing or inhibiting multidrug resistance.
