1517-15-3Relevant articles and documents
The first synthesis of spirocyclic sulfates from tertiary cyclopropanols and their reaction with normant homocuprates
Shklyaruck, Denis G.,Fedarkevich, Artsiom N.,Kozyrkov, Yurii Yu.
, p. 1855 - 1858 (2014)
Spirocyclic sulfates of 2- and 3-(hydroxyalkyl)cyclopropanols, obtainable through the Kulinkovich reaction from β-and γ-hydroxy carboxylic acid esters, respectively, were synthesized for the first time. The possibility of regio- and stereoselective alkyla
Howton,Buchman
, p. 4011 (1956)
Selective α-Methylation of Ketones
Frolov, Andriy I.,Ostapchuk, Eugeniy N.,Pashenko, Alexander E.,Chuchvera, Yaroslav O.,Rusanov, Eduard B.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.
, p. 7333 - 7346 (2021/06/28)
The convenient and scalable preparative approach for the two-step α-methylation of ketones is described. The optimized protocols for regioselective preparation of enaminones with further diastereoselective and functional groups tolerant hydrogenation to α-methylketones are developed. The scope and limitations of the proposed methodology are discussed. The advantages compared to known procedures are demonstrated. The unexpected role of acetone in the hydrogenation is suggested. The evaluation of the method for both early building block synthesis and late-stage CH-functionalization is shown. The elaborate procedures' preparability and scalability are demonstrated by the synthesis of several α-methyl ketones up to 100 g amount.
Pulling the levers of photophysics: How structure controls the rate of energy dissipation
Kuhlman, Thomas S.,Pittelkow, Michael,Solling, Theis I.,Moller, Klaus B.
supporting information, p. 2247 - 2250 (2013/03/28)
Internal conversion: The energy difference between the Franck-Condon and equilibrium geometries and the vibrational frequency of one or a few modes determine the relative importance of adiabatic and nonadiabatic dynamics and thus the rate of electronic en
