530102-41-1

Basic information

• Product Name: (αR,1S,2S)-2-methyl-1-(1-phenylethylamino)cyclobutanecarboxamide
• CAS NO: 530102-41-1
• Molecular Weight: 232.326
• Mol File: 530102-41-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (αR,1S,2S)-2-methyl-1-(1-phenylethylamino)cyclobutanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (αR,1S,2S)-2-methyl-1-(1-phenylethylamino)cyclobutanecarboxamide(530102-41-1)
• EPA Substance Registry System: (αR,1S,2S)-2-methyl-1-(1-phenylethylamino)cyclobutanecarboxamide(530102-41-1)

Safety Data

• Hazardous Substances Data: 530102-41-1(Hazardous Substances Data)

Upstream product

• 530102-39-7 [2-Methyl-cyclobut-(E)-ylidene]-((R)-1-phenyl-ethyl)-amine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 1517-15-3 2-methylcyclobutanone 
• 530102-40-0 2-methyl-1-(1-phenylethylamino)cyclobutane carbonitrile 

Relevant articles and documents

Cyclobutane amino acids (CBAAs): Asymmetric Strecker synthesis of enantiopure cis- and trans-2,4-methanovalines

Synthesis of enantiopure 2,4-methanovalines has been achieved by means of asymmetric Strecker synthesis starting from racemic 2-methylcyclobutanone. The trans-configured α-amino acids were obtained from cyanide additions carried out in methanol, whereas the cis-configured 2,4-methanovalines were accessible via reactions in hexane. Relative stereochemistry was elucidated from NOESY experiments, while absolute configurations were assigned from X-ray crystallographic analysis.