15174-69-3 Usage
Description
4-Hydroxy-3-methylbenzaldehyde, also known as vanillin, is an organic compound that is a derivative of benzaldehyde. It is characterized by its distinct aromatic smell and is the primary component responsible for the flavor and fragrance of vanilla. This versatile compound is widely used in various industries due to its unique properties and applications.
Uses
Used in Pharmaceutical Industry:
4-Hydroxy-3-methylbenzaldehyde is used as a key intermediate in the synthesis of various pharmaceutical compounds. It plays a crucial role in the preparation of benzothiazole Schiff bases, which have been found to exhibit significant antitumor activity against cervical cancer. The compound's ability to modulate cellular processes and inhibit tumor growth makes it a valuable asset in the development of novel cancer treatments.
Used in Cosmetics and Flavor Industry:
4-Hydroxy-3-methylbenzaldehyde is used as a natural flavoring agent and fragrance component in the cosmetics and flavor industry. Its characteristic vanilla scent and taste make it an ideal additive for a wide range of products, including perfumes, candles, and food items. The compound's natural origin and pleasant aroma contribute to its popularity in these applications.
Used in Chemical Synthesis:
4-Hydroxy-3-methylbenzaldehyde is also used as a starting material in the synthesis of various organic compounds, such as novel pyrimidine derivatives. These derivatives have been found to possess potent antibacterial properties against both gram-positive and gram-negative bacteria, making them valuable in the development of new antimicrobial agents.
Check Digit Verification of cas no
The CAS Registry Mumber 15174-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,7 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15174-69:
(7*1)+(6*5)+(5*1)+(4*7)+(3*4)+(2*6)+(1*9)=103
103 % 10 = 3
So 15174-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O2/c1-6-4-7(5-9)2-3-8(6)10/h2-5,10H,1H3
15174-69-3Relevant articles and documents
Ruthenium(VIII)-Catalyzed ipso-Dearomative Spiro-Etherification and Spiro-Amidation of Phenols
Sarkar, Debayan,Rout, Nilendri
supporting information, p. 4132 - 4136 (2019/06/14)
An open air ruthenium(VIII)-catalyzed oxidative spiro-etherification as well as spiro-amidation of phenols has been performed. The transformation works satisfactorily with both phenols and naphthols and thus exhibits a wide range of flexibility. The catalysis is performed in open air at room temperature with a yield of ≤95%.
Highly practical and cost-efficient synthesis of telmisartan: An antihypertensive drug
Wang, Ping,Zheng, Guo-Jun,Wang, Ya-Ping,Wang, Xiang-Jing,Wei, He-Geng,Xiang, Wen-Sheng
experimental part, p. 2509 - 2512 (2012/04/11)
A novel and cost-efficient strategy for synthesis of an antihypertensive drug telmisartan, a substituted bis-benzimidazole derivative, is described. The key strategy is the construction of bis-benzimidazole 4 by reductive cyclization of o-nitroanilines 11 with butyl aldehyde and cyclocondensation of aromatic aldehydes 9 with o-phenylenediamine, then N-alkylation is allowed to give the target compound telmisartan after hydrolysis. The simple operation and workup procedure, along with the low production costs, make it suitable for industrial production and will benefits those with cardiovascular disease.
Electrosynthesis of aromatic aldehydes by palladium-catalyzed carbonylation of aryl iodides in the presence of formic acid
Carelli, Italo,Chiarotto, Isabella,Cacchi, Sandro,Pace, Paola,Amatore, Christian,Jutand, Anny,Meyer, Gilbert
, p. 1471 - 1473 (2007/10/03)
The palladium-catalyzed electrocarbonylation of aryl halides performed in the presence of formic acid under one atmosphere of carbon monoxide affords aromatic aldehydes in good to high yields.