152192-96-6

Basic information

• Product Name: (2-HYDROXY-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (2-HYDROXY-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER;2-(N-BOC-PROPYLAMINO)ETHANOL;N-Boc-N-n-propylethanolaMine, 96%;tert-Butyl 2-hydroxyethyl(propyl)carbaMate
• CAS NO: 152192-96-6
• Molecular Formula: C₁₀H₂₁NO₃
• Molecular Weight: 203.28
• Mol File: 152192-96-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-HYDROXY-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-HYDROXY-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER(152192-96-6)
• EPA Substance Registry System: (2-HYDROXY-ETHYL)-PROPYL-CARBAMIC ACID TERT-BUTYL ESTER(152192-96-6)

Safety Data

• Hazardous Substances Data: 152192-96-6(Hazardous Substances Data)

Usage

General Description

(2-Hydroxy-ethyl)-propyl-carbamic acid tert-butyl ester is a chemical compound that is used in the production of various products, including pesticides, lubricants, and pharmaceuticals. It is commonly referred to as diethyltoluamide (DEET) and is known for its insect repellent properties. DEET is a widely used component in mosquito repellents and has been found to be highly effective in protecting against mosquito bites. Additionally, it is used in the production of plasticizers, which are substances added to plastics to increase their flexibility, durability, and resistance to heat. DEET is considered to be a versatile chemical with a wide range of industrial applications.

Upstream product

• 16369-21-4 N-(2-hydroxyethyl)-N-propylamine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 850724-00-4 3-{4-[2-(tert-butoxycarbonyl-propyl-amino)-ethoxy]-phenyl}-propionic acid methyl ester 
• 850724-03-7 3-[4-(2-propylamino-ethoxy)-phenyl]-propionic acid methyl ester 
• 850724-05-9 3-{4-[2-(propyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-propionic acid methyl ester 
• 1434047-86-5 tert-butyl 2-(5-bromopyridin-3-yloxy)ethyl(propyl)carbamate 
• 1434047-73-0 N-(2-(5-(phenylethynyl)pyridin-3-yloxy)ethyl)propan-1-amine 
• 1434047-87-6 tert-butyl 2-(5-(phenylethynyl)pyridin-3-yloxy)ethyl(propyl)carbamate 

Relevant articles and documents

Structure-property relationships of antibacterial amphiphilic polymers derived from 2-aminoethyl acrylate

The findings from the investigation of an ensemble of amphiphilic polymers derived from 2-aminoethyl acrylate establish significant effects of variation in the topographical position of the cationic center and hydrophobic segments on their biological activities. For example, the isomeric polymer pair of poly(6-aminohexylacrylate) and poly(2-(butylamino)ethyl acrylate) show striking differences in their biological activities, with the former having biological activities orders of magnitude higher. The trend of the activities of alkyl tails attached to the charge center shows an abrupt increase in biological activity at butyl length in the series of methyl to butyl tail. The distribution and interaction of the charge center in the chain domain is one of the main parameters in influencing polymer activities. Within the 2-aminoethyl acrylate system of homo- and copolymer, the homopolymer has its cationic centers closely distributed along the amphiphilic macromolecular chain with proximity to the backbone leading to rigid conformations not conducive to the attachment of the polymer to the cell surface. In copolymers, the incorporation of uncharged counits increases the distance between the cationic centers, resulting in significant reduction of charge repulsion and thus enhancing the flexibility of the chain conformation. This is conducive for polymer-cell association, leading to a remarkable surge in orders of magnitude of biological activity but with low selectivity against bacteria over red blood cells.

Mono-(BOC)-protected diamines. Synthesis of tert-butyl-N-alkyl-N-(2-aminoethyl)carbamates and tert-butyl-N-[2-(alkylamino)ethyl] carbamates

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