152427-73-1

Basic information

• Product Name: (5R,6R,7S,9R,13S,14R)-7-Acetyl-17-benzyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan
• Synonyms: (5R,6R,7S,9R,13S,14R)-7-Acetyl-17-benzyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan
• CAS NO: 152427-73-1
• Molecular Weight: 457.569
• Mol File: 152427-73-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R,6R,7S,9R,13S,14R)-7-Acetyl-17-benzyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,6R,7S,9R,13S,14R)-7-Acetyl-17-benzyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan(152427-73-1)
• EPA Substance Registry System: (5R,6R,7S,9R,13S,14R)-7-Acetyl-17-benzyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan(152427-73-1)

Safety Data

• Hazardous Substances Data: 152427-73-1(Hazardous Substances Data)

Upstream product

• 2579-67-1 northebaine 
• 100-44-7 benzyl chloride 
• 78-94-4 methyl vinyl ketone 
• 72221-15-9 N-Benzyl-northebain 

Downstream Products

• 152427-77-5 (5R,6R,7S,9R,13S,14S)-7-Acetyl-17-cyclopropylmethyl-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-6,14-ethanomorphinan 
• 52485-79-7 Buprenorphine 
• 14357-78-9 diprenorphine 

Relevant articles and documents

Preparation of 6,14-Ethenomorphinane Derivatives

Buprenorphine (5j) and diprenorphine (5k) were synthesized from N-formyl-northebaine (1c) and N-benzyl-northebaine (1d) via new intermediates.N-cyclopropylmethyl-dihydronorthevinone 3d is a suitable compund for the synthesis of both 5j and 5k.We carried out detailed (1)H- and (13)C-NMR analysis of the new compounds. Key words: Buprenorphine; diprenorphine; rotamers, N-CHO; morphinane derivatives; alkaloids.