15246-95-4Relevant articles and documents
Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicity
Szcz??niak-Si?ga, Berenika M.,Mogilski, Szczepan,Wiglusz, Rafa? J.,Janczak, Jan,Maniewska, Jadwiga,Malinka, Wies?aw,Filipek, Barbara
, p. 1619 - 1628 (2019)
Gastrotoxicity continues to be a major issue in therapy with nonsteroidal anti-inflammatory drugs (NSAIDs). Medicine is yet to develop absolutely safe analgesics. Numerous strategies are employed to discover new, safer NSAIDs, for example selective inhibi
Synthesis and α-glucosidase inhibition activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2h-benzo[e][1,2]thiazin-2-yl]-n-arylacetamides: An in silico and biochemical approach
Ahmad, Matloob,Ashfaq, Usman Ali,Aslam, Sana,Hussain, Muzammil,Lee, Dae Sung,Muddassar, Muhammad,Saddique, Furqan Ahmad,Sultan, Sadia,Taj, Saman,Zaki, Magdi E. A.
, (2021/06/08)
Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people worldwide. Insufficient insulin production causes an increase in blood glucose level that results in DM. To lower the blood glucose level, various drugs are employed th
Synthesis and biological evaluation as well as in silico studies of arylpiperazine-1,2-benzothiazine derivatives as novel anti-inflammatory agents
Szcz??niak-Si?ga, Berenika M.,Wiatrak, Benita,Czy?nikowska, ?aneta,Janczak, Jan,Wiglusz, Rafal J.,Maniewska, Jadwiga
, (2020/12/02)
Novel arylpiperazine-1,2-benzothiazine derivatives have been designed and synthesized as potential anti-inflammatory agents. Their structure and properties have been studied using spectroscopic techniques (1H NMR, 13C NMR, FT-IR), MS