152570-22-4Relevant articles and documents
Acetylene Chemistry. Part 27. Palladium Catalysed C-C Bond Formation Between Quinoline and Mono-substituted Alkynes: Synthesis of 4-Alkynyl-2-bromoquinolines
Reisch, Johannes,Gunaherath, G. M. Kamal B.
, p. 1057 - 1060 (2007/10/02)
Six new 4-alkynyl-2-bromoquinolines have been synthesised via palladium catalysed C-C bond formation between 2,4-dibromoquinoline and mono-substituted alkynes.Position of the alkyne substituent was confirmed to be at C-4 by an nOe experiment on some methoxy derivatives prepared by nucleophilic displacement of bromo substituent.