152700-41-9Relevant articles and documents
Site Selectivity and Regioselectivity of Nitrile Oxide Cycloadditions to N,N-Diarylaminoallenes
Broggini, Gianluigi,Molteni, Giorgio,Zecchi, Gaetano
, p. 1263 - 1278 (2007/10/02)
N,N-Diarylaminoallenes were synthesized by isomerisation of the corresponding propargyl derivatives and submitted to reaction with 3,5-dichloro-2,4,6-trimethylbenzonitrile oxide. 5-Diarylamino-4-methylene-4,5-dihydroisoxazoles were formed with full site selectivity and regioselectivity. These cycloadducts were susceptible to nitrile oxide cycloaddition onto the exocyclic double bond as well as to acid-promoted amino-Claisen rearrangement.