153390-68-2

Basic information

• Product Name: 2-(2,3-diMethoxyphenyl)propan-2-ol
• Synonyms: 2-(2,3-diMethoxyphenyl)propan-2-ol
• CAS NO: 153390-68-2
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24294
• Mol File: 153390-68-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 97 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 1.060±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: Chloroform, Dichloromethane, Ethyl acetate, Methanol
• PKA: 14.30±0.29(Predicted)
• CAS DataBase Reference: 2-(2,3-diMethoxyphenyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3-diMethoxyphenyl)propan-2-ol(153390-68-2)
• EPA Substance Registry System: 2-(2,3-diMethoxyphenyl)propan-2-ol(153390-68-2)

Safety Data

• Hazardous Substances Data: 153390-68-2(Hazardous Substances Data)

Usage

Description

2-(2,3-diMethoxyphenyl)propan-2-ol is an organic compound with the molecular formula C11H16O3. It is a colorless to pale yellow liquid with a distinct aromatic odor. 2-(2,3-diMethoxyphenyl)propan-2-ol is characterized by the presence of a phenyl ring with two methoxy groups at the 2nd and 3rd positions, and a propyl group attached to the 2nd carbon of the phenyl ring. Its chemical structure endows it with unique properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
2-(2,3-diMethoxyphenyl)propan-2-ol is used as an intermediate for the synthesis of Miltirone (M344500), an active component in Salvia miltiorrhiza. Miltirone has demonstrated potential as a phytotherapeutic agent in the treatment of alcohol dependence. It works by inhibiting the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons, thus helping to alleviate the symptoms of alcohol withdrawal and reducing the risk of relapse.

Upstream product

• 2150-42-7 methyl 2,3-dimethoxybenzoate 
• 75-16-1 methylmagnesium bromide 
• 91-16-7 1,2-dimethoxybenzene 
• 67-64-1 acetone 
• 1521-38-6 2,3-dimethoxybenzoic acid 
• 86-51-1 2,3-dimethyoxybenzaldehyde 

Downstream Products

• 181016-77-3 2‐(5‐bromo‐2,3‐dimethoxyphenyl)propan‐2‐ol 
• 850254-51-2 5‐bromo‐1‐isopropyl‐2,3‐dimethoxybenzene 
• 181016-78-4 5-bromo-1-isopropenyl-2,3-dimethoxybenzene 
• 850254-61-4 4-[(E)-2-(3-Isopropyl-4,5-dimethoxy-phenyl)-vinyl]-3,3,4-trimethyl-cyclohexanone 
• 850254-56-7 4-[2-hydroxy-2-(3-isopropyl-4,5-dimethoxy-phenyl)-ethyl]-3,3,4-trimethyl-cyclohexanone 
• 850254-59-0 3-[(E)-2-(3-Isopropyl-4,5-dimethoxy-phenyl)-vinyl]-3,4,4-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 850254-52-3 3-[2-(3-isopropyl-4,5-dimethoxy-phenyl)-2-methoxycarbonyloxy-ethyl]-3,4,4-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 850254-57-8 5-[2-(3-isopropyl-4,5-dimethoxy-phenyl)-2-methoxycarbonyloxy-ethyl]-4,4,5-trimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester 
• 2138-48-9 3-isopropylbenzene-1,2-diol 

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