153391-51-6Relevant articles and documents
Br?nsted acid mediated cyclizations of ortho-aryl(ethynyl)pyrimidines
Shestakov, Aleksandr N.,Pankova, Alena S.,Golubev, Pavel,Khlebnikov, Alexander F.,Kuznetsov, Mikhail A.
, p. 3939 - 3948 (2017/06/14)
A high-yielding procedure for the synthesis of 5-aryl-4-(arylethynyl)pyrimidines from easily available 2-aryl-3-hydroxyacrylates is reported. These pyrimidines readily undergo cyclization in strong Br?nsted acids and, depending on the substitution in alky