901311-77-1

Basic information

• Product Name: 2-CHLORO-4-METHOXY-5-PHENYL-PYRIMIDINE
• Synonyms: 2-CHLORO-4-METHOXY-5-PHENYL-PYRIMIDINE
• CAS NO: 901311-77-1
• Molecular Formula: C₁₁H₉ClN₂O
• Molecular Weight: 0
• Mol File: 901311-77-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-CHLORO-4-METHOXY-5-PHENYL-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-METHOXY-5-PHENYL-PYRIMIDINE(901311-77-1)
• EPA Substance Registry System: 2-CHLORO-4-METHOXY-5-PHENYL-PYRIMIDINE(901311-77-1)

Safety Data

• Hazardous Substances Data: 901311-77-1(Hazardous Substances Data)

Upstream product

• 57054-92-9 5-bromo-2-chloro-4-methoxypyrimidine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 37428-97-0 2,4,5-triphenylpyrimidine 
• 153391-51-6 4-chloro-2,5-diphenylpyrimidine 
• 901311-78-2 4-methoxy-2,5-diphenylpyrimidine 

Relevant articles and documents

Microwave-assisted, efficient and regioselective Pd-catalyzed C-phenylation of halopyrimidines

We herein report that flash heating microwave irradiation is a helpful tool in the formation of arylpyrimidines from the corresponding halopyrimidines. The palladium-catalyzed cross-coupling reactions of 2,4-di- and 2,4,5-trihalopyrimidines with phenylboronic acid under the above conditions are described. By use of the appropriate catalyst and the adequate halopyrimidine, good regioselectivity can be achieved in the 2-, 4-, or 5-positions of the heterocycle. In addition, we show that this methodology is ameneable for the stepwise preparation of mono-, di-, and triphenylpyrimidines.