154656-95-8Relevant articles and documents
Hydroaminomethylation of Olefins with Aminomethyltrifluoroborate by Photoredox Catalysis
Miyazawa, Kazuki,Koike, Takashi,Akita, Munetaka
, p. 2749 - 2755 (2016/02/18)
A photocatalytic hydroaminomethylation of olefins with N-protected aminomethyltrifluoroborates has been developed. This methodology provides a new strategy for the introduction of a primary aminomethyl group onto electron-deficient C=C bonds. This reaction constitutes a facile entry into synthetically useful γ-aminobutyric acid (GABA) derivatives such as baclofen.