154713-23-2Relevant articles and documents
Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity
Kamal, Ahmed,Ramulu,Srinivas,Ramesh,Kumar, P. Praveen
, p. 4791 - 4794 (2007/10/03)
Two types of benzimidazoles have been synthesized and linked to DC-81 at C8-position through different alkyl chain spacers. These PBD conjugates have exhibited remarkable DNA-binding affinity, and a representative compound shows promising in vitro antican