774221-44-2

Basic information

• Product Name: (2S)-N-{3-(4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenoxy)propoxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal
• Synonyms: (2S)-N-{3-(4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenoxy)propoxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal
• CAS NO: 774221-44-2
• Molecular Weight: 748.968
• Mol File: 774221-44-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S)-N-{3-(4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenoxy)propoxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-N-{3-(4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenoxy)propoxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal(774221-44-2)
• EPA Substance Registry System: (2S)-N-{3-(4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenoxy)propoxy-5-methoxy-2-nitrobenzoyl}pyrrolidine-2-carboxaldehyde diethyl thioacetal(774221-44-2)

Safety Data

• Hazardous Substances Data: 774221-44-2(Hazardous Substances Data)

Upstream product

• 154713-23-2 4-[6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo[d]imidazol-2-yl]phenol 
• 343308-55-4 (2S)-N-[4-(3-bromopropoxy)-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 23491-48-7 5-(4-methylpiperazine-1-yl)-2-nitroaniline 
• 54998-08-2 4-(4-methylpiperazino)-1,2-diaminobenzene 
• 1635-61-6 5-chloro-2-nitroaniline 
• 109-01-3 1-methyl-piperazine 

Downstream Products

• 774221-50-0 (2S)-N-{3-(4-(6-(4-methylhexahydro-1-pyrazinyl)-1H-benzo [d]imidazol-2-yl)phenoxy) propoxy-5-methoxy-2-aminobenzoyl1}pyrrolidine2-carboxaldehyde diethyl thioacetal 

Relevant articles and documents

PROCESS FOR PREPARING PYRROLO[2, 1-c] [1, 4] BENZODIAZEPINE HYBRIDS

Novel pyrrolo[2, 1-c] [1, 4] benzodiazepine hybrids as well as processes for the proepartion of novel pyrrolo [2, 1-c] [1, 4] benzodiazepine hybrids are disclosed. More particularly, present invention relates to a process for the preparation of novel pyrr

Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity

Two types of benzimidazoles have been synthesized and linked to DC-81 at C8-position through different alkyl chain spacers. These PBD conjugates have exhibited remarkable DNA-binding affinity, and a representative compound shows promising in vitro antican