15482-17-4

Basic information

• Product Name: 1-Propanone, 2-hydroxy-1-(4-methoxyphenyl)-2-methyl-
• Synonyms: 1-(4'-methoxyphenyl)-2-hydroxy-2-methyl-propanone;2-hydroxy-1-(4-methoxy-phenyl)-2-methyl-propan-1-one;2-hydroxy-1-(4-methoxyphenyl)-2-methylpropan-1-one;1-p-Anisyl-2-hydroxy-2-methyl-propanon-(1);2-Hydroxy-1-(4-methoxy-phenyl)-2-methyl-propan-1-on;1-(4'-Methoxyphenyl)-2-hydroxy-2-methyl-propanon-(1)
• CAS NO: 15482-17-4
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 15482-17-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 54 - 55 °C (cyclohexane)
• CAS DataBase Reference: 1-Propanone, 2-hydroxy-1-(4-methoxyphenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-hydroxy-1-(4-methoxyphenyl)-2-methyl-(15482-17-4)
• EPA Substance Registry System: 1-Propanone, 2-hydroxy-1-(4-methoxyphenyl)-2-methyl-(15482-17-4)

Safety Data

• Hazardous Substances Data: 15482-17-4(Hazardous Substances Data)

Usage

Physical state

Pale yellow liquid

Odor

Sweet, floral

Usage

Fragrance ingredient in cosmetic and personal care products, perfumes, soaps, and lotions

Functional groups

Ketone, hydroxy, methoxy

Aromatic properties

Distinct due to the presence of the functional groups attached to the phenyl ring

Industrial application

Synthesis of various pharmaceuticals and potential use in the pharmaceutical industry

Upstream product

• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 18228-46-1 1-(p-methoxyphenyl)-2-methylpropan-1-ol 
• 261930-06-7 1-(4-methoxyphenyl)-1,2-dihydroxy-2-methylpropane 
• 2040-20-2 4-methoxyisobutyrophenone 

Downstream Products

• 15482-31-2 1-hydroxy-1-methyl-1-(4'-methoxyphenyl)-2-propanone 

Relevant articles and documents

Α - hydroxy ketone compound low priced high-efficient synthetic method

The invention discloses a cheap and efficient synthesis method of an alpha-hydroxyketone compound. The synthesis method is characterized in that a carbonyl compound undergoes an oxidation hydroxylation reaction at 10-120DEG C under normal pressure with iodine simple substance, N-bromosuccimide, copper bromide, bromine simple substance, hydrogen bromide, N-iodosuccimide or hydrogen iodide as a catalyst, sulfoxide as an oxidant, water or sulfoxide as a hydroxy source and sulfoxide, ethyl acetate, N,N-dimethyl formamide, acetonitrile, toluene, 1,4-dioxane, 1,2-dichloroethane, tetrahydrofuran or H2O as a solvent, and converts into the alpha-hydroxyketone compound in a high selectivity manner. Compared with traditional synthesis methods, the method disclosed in the invention has the advantages of simple operation, high yield, simple conditions, easy purification, small waste discharge amount, simple reaction apparatus, and easy industrial production. The method has wide applicability and can be used for synthesizing various alpha-hydroxyketone compounds.

I2- or NBS-catalyzed highly efficient α-hydroxylation of ketones with dimethyl sulfoxide

An efficient method for the direct preparation of high synthetic valuable α-hydroxycarbonyls is described. The simple and readily available I2 or NBS was used as catalyst. DMSO acts as the oxidant, oxygen source, and solvent. A diverse range of tertiary Csp3-H bonds as well as more challenging secondary Csp3-H bonds could be hydroxylated in this transformation. The reaction is mild, less toxic and easy to perform.

Oxygen-containing titanocenes, and the use thereof

Titanocenes of the formula I STR1 in which R1 are cyclopentadienyl? groups and R2 and R3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by an acyloxy group are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.