154928-39-9Relevant articles and documents
Solid-phase synthesis of oligonucleotides containing a bipyridine ligand at the 3′-3′ inversion of polarity site
Galeone, Aldo,Mayol, Luciano,Oliviero, Giorgia,Rigano, Daniela,Varra, Michela
, p. 383 - 386 (2001)
The preparation of a solid support useful for the synthesis of oligonucleotides with a 3′-3′ inversion of polarity, via a linker containing a chelating molecule, namely 2,2′-bipyridine, is described.
Phosphoramidate and phosphorothiomidate oligomeric compounds
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, (2008/06/13)
Compounds are provided having structure (I), wherein the L groups are backbone segments, the Y and T groups are functional groups for interacting with target molecules of interest, the X groups are oxygen or sulfur and the E groups are H, conjugate groups or intermediate groups used during the synthesis of the compounds and wherein the compounds are prepared using H phosphonate type chemistry wherein the functional groups are added during an oxidation step or during a coupling step. STR1
