154928-41-3Relevant articles and documents
Modified oligonucleotides and compound that can be used for synthesizing same
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Paragraph 0129-0130, (2020/12/08)
The present disclosure falls within the field of biomedical technology, and in particular relates to modified oligonucleatides and a compound that can be used for synthesizing same and a method for modifying oligonucleotides. The present disclosure also relates to the use of the modified oligonucleotides for preventing and/or treating diseases associated with the liver in a subject.
New phosphoramidite derivatives for the preparation of oligonucleotides containing a hydrazide group in any specified position of the oligonucleotide chain
Antsypovich,Oretskaya,Von Kiedrowski
, p. 2671 - 2681 (2007/10/03)
A new versatile method for the preparation of oligonucleotides containing hy drazide groups in any position of the oligonucleotide chain by standard phosphoramidite automated oligonucleotide synthesis is proposed. The method is based on the use of a serie
Synthesis and hybridization properties of sugar-modified oligonucleotides
Sharma, Ashwani K.,Kumar, Pradeep,Gupta, Kailash C.
, p. 3643 - 3649 (2007/10/03)
L-Threoninol-derived acyclic nucleotide monomers were prepared and incorporated into oligonucleotides at preselected positions via phosphoramidite chemistry. Hybridization properties of these modified oligonucleotides with the corresponding natural oligom