180720-86-9

Basic information

• Product Name: N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)ethyl}-2,2,2-trifluoroacetamide
• Synonyms: N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)ethyl}-2,2,2-trifluoroacetamide
• CAS NO: 180720-86-9
• Molecular Weight: 489.491
• Mol File: 180720-86-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)ethyl}-2,2,2-trifluoroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)ethyl}-2,2,2-trifluoroacetamide(180720-86-9)
• EPA Substance Registry System: N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)ethyl}-2,2,2-trifluoroacetamide(180720-86-9)

Safety Data

• Hazardous Substances Data: 180720-86-9(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 180720-85-8 N-(1,3-dihydroxypropan-2-yl)-2,2,2-trifluoroacetamide 

Downstream Products

• 154928-41-3 2-amino-1-O-(4,4'-dimethoxytrityl)propane-1,3-diol 
• 176755-94-5 3-dimethoxytrityloxy-2-<amino>propanol 
• 227798-08-5 ({[2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethyl]-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-methyl)-phosphonic acid diphenyl ester 
• 227798-07-4 {[2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethylamino]-methyl}-phosphonic acid diphenyl ester 
• 227798-06-3 2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethylamine 
• 415711-31-8 2-(1,3-dihydro-5-methyl-2,4-dioxopyrimidin-1-yl)-N-{2-[(4,4'-dimethoxytrityl)oxy]-1-(hydroxymethyl)-ethyl}acetamide 
• 924884-94-6 diethyl 2-tert-butyl(dimethyl)silyloxymethyl-2-[2-(4-{N-[1-(4,4'-dimethoxy)trityloxy-3-hydroxypropan-2-yl]carbamoyloxy}butyryl)hydrazino]carbonyloxymethylmalonate 

Relevant articles and documents

New phosphoramidite derivatives for the preparation of oligonucleotides containing a hydrazide group in any specified position of the oligonucleotide chain

A new versatile method for the preparation of oligonucleotides containing hy drazide groups in any position of the oligonucleotide chain by standard phosphoramidite automated oligonucleotide synthesis is proposed. The method is based on the use of a serie

Synthesis and hybridization properties of sugar-modified oligonucleotides

L-Threoninol-derived acyclic nucleotide monomers were prepared and incorporated into oligonucleotides at preselected positions via phosphoramidite chemistry. Hybridization properties of these modified oligonucleotides with the corresponding natural oligom