155096-16-5Relevant articles and documents
Isolation, Structure, and Synthesis of Dolastatin D, a Cytotoxic Cyclic Depsipeptide from the Sea Hare Dolabella auricularia
Sone, Hiroki,Nemoto, Takayuki,Ishiwata, Hiroyuki,Ojika, Makoto,Yamada, Kiyoyuki
, p. 8449 - 8452 (1993)
Dolastatin D (1), a cytotoxic cyclic depsipeptide possessing the novel β-amino acid (2R,3R)-3-amino-2-methylbutanoic acid as a component, has been isolated from the Japanese sea hare Dolabella auricularia.The absolute stereostructure of 1 was elucidated on the basis of spectroscopic analysis and chemical degradation and was further confirmed by synthesis.