7622-21-1

Basic information

• Product Name: BENZYL (S)-(-)-2-HYDROXY-3-PHENYLPROPIONATE
• Synonyms: BENZYL (S)-(-)-2-HYDROXY-3-PHENYLPROPIONATE
• CAS NO: 7622-21-1
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.3
• Product Categories: Chiral Building Blocks;Esters;Organic Building Blocks
• Mol File: 7622-21-1.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 288 °C(lit.)
• Flash Point: 113 °C
• Appearance: /
• Density: 1.142 g/mL at 25 °C(lit.)
• Vapor Pressure: 3.51E-07mmHg at 25°C
• Refractive Index: n20/D 1.558(lit.)
• CAS DataBase Reference: BENZYL (S)-(-)-2-HYDROXY-3-PHENYLPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL (S)-(-)-2-HYDROXY-3-PHENYLPROPIONATE(7622-21-1)
• EPA Substance Registry System: BENZYL (S)-(-)-2-HYDROXY-3-PHENYLPROPIONATE(7622-21-1)

Safety Data

• Hazardous Substances Data: 7622-21-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H16O3/c17-15(11-13-7-3-1-4-8-13)16(18)19-12-14-9-5-2-6-10-14/h1-10,15,17H,11-12H2/t15-/m0/s1

Upstream product

• 20312-36-1 L-3-phenyllactic acid 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 2978-10-1 N,N'-diisopropyl-O-benzyl isourea 
• 63-91-2 L-phenylalanine 
• 828-01-3 phenyllactic acid 
• 534-17-8 caesium carbonate 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 
• 93434-59-4 3-Phenyl-2(S)-hydroxypropionic acid benzyl ester 
• 35016-63-8 (S)-2-bromo-3-phenylpropionic acid 
• 828-01-3 D-phenyllactic acid 
• 673-06-3 D-(R)-phenylalanine 

Downstream Products

• 155096-16-5 (S)-2-tert-Butoxycarbonylamino-3-methyl-butyric acid (S)-1-benzyloxycarbonyl-2-phenyl-ethyl ester 
• 146953-71-1 (S)-3-phenyl-2-trifluoromethanesulfonyloxy-propionic acid benzyl ester 
• 111437-25-3 benzyl (R)-(+)-3-phenyl-2-(trifluoromethylsulfonyloxy)propanoate 
• 153052-70-1 benzyl N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactate 
• 105852-84-4 benzyl O-pivaloyl-L-phenyllactate 
• 168099-79-4 O-benzyl O'-(benzyl L-phenyl-lactate) H-phosphonate 
• 212117-43-6 (S)-2-{(R)-3-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoyloxy]-2-oxo-azepan-1-yl}-4-methyl-pentanoic acid (R)-1-benzyloxycarbonyl-2-phenyl-ethyl ester 
• 342418-56-8 (R)-1-Phenyl-3-vinyl-pent-4-ene-2,3-diol 
• 339201-15-9 (R)-N-benzyloxycarbonyl-N-phthalimidophenylalanine benzyl ester 

Relevant articles and documents

Characterization of binding affinities in a chromatographic system by suspended state HR/MAS NMR spectroscopy

In the current work a racemate of (R)-and (S)-benzylmandelate was separated with a stereoselective polysaccharide-based chiral stationary phase by HPLC. To elucidate the occurring chiral molecular recognition processes in the heterogeneous system used, NMR spectroscopy was chosen under high resolution/magic angle spinning (HR/MAS) NMR conditions in the suspended state. Therefore, and as a proof of concept, a combination of several NMR methods such as spin - lattice relaxation time (T1) measurements (T1), the saturation transfer difference, and the 2D experiment of the transferred nuclear overhauser enhancement spectroscopy technique were applied. With HR/MAS NMR it is feasible to combine NMR and chromatography to achieve further insights into the separation process. Copyright

ENDOPARASITIC DEPSIPEPTIDES

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof (1) wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Learning from Peptides to Access Functional Precision Polymer Sequences

Functional precision polymers based on monodisperse oligo(N-substituted acrylamide)s and oligo(2-substituted-α-hydroxy acid)s have been synthesized. The discrete sequences originate from a direct translation of side-chain functionality sequences of a peptide with well-studied properties. The peptide was previously selected to solubilize the photosensitizer meta-tetra(hydroxyphenyl)chlorin. The resulting peptidomimetic formulation additives preserve the drug solubilization and release characteristics of the parent peptide. In some cases, superior properties are obtained, reaching up to 40 % higher payloads and 27-times faster initial drug release.