155112-29-1Relevant articles and documents
The first example of trimethylsilyl methylenenitronate reacting with aldehydes under an apparent Mukaiyama nitro-aldol reaction
MacDonald, Frank K.,Carneiro, Karina M.M.,Pottie, Ian R.
, p. 891 - 893 (2011)
Trimethylsilyl methylenenitronate reacts with both aliphatic and aromatic aldehydes in the presence of catalytic amounts of scandium(III) triflate to form the Henry reaction products in low (25%) to good yields (77%). This is the first example of this silyl nitronate undergoing a nitro-aldol reaction under an acid environment.
METAL SALT-PROMOTED ALDOL REACTION OF SILYL ENOL ETHERS WITH ALDEHYDES
Chini, Marco,Crotti, Paolo,Gardelli, Cristina,Minutolo, Filippo,Pineschi, Mauro
, p. 673 - 676 (2007/10/02)
Simple metal salts such as lithium perchlorate and zinc triflate effectively promote aldol condensation between silyl enol ethers and aldehydes or acetals in non-protic solvents to yield the O-protected aldols in good yields. A slight preference for the syn aldol is observed when a prochiral silyl enol ether reacts with benzaldehyde, a complete syn stereoselectivity being obtained only in the case of the hindered silyl enol ether 14. The method appears to be simple and competitive with other ones previously described.
