17510-46-2

Basic information

• Product Name: (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE
• Synonyms: (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE;(1-TERT-BUTYLVINYLOXY)TRIMETHYLSILANE;PINACOLONE TRIMETHYLSILYL ENOL ETHER;T-BUTYLVINYLOXYTRIMETHYLSILANE;TERT-BUTYLVINYLOXYTRIMETHYLSILANE;(2,2-Dimethyl-1-methylenepropoxy)trimethylsilane, 3,3-Dimethyl-2-trimethylsiloxy-1-butene, Pinacolone enol trimethylsilyl ether;(1-tert-Butylvinyloxy)triMethylsilane 98%
• CAS NO: 17510-46-2
• Molecular Formula: C₉H₂₀OSi
• Molecular Weight: 172.34
• Mol File: 17510-46-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 140-142 °C(lit.)
• Flash Point: 76 °F
• Appearance: /
• Density: 0.798 g/mL at 25 °C(lit.)
• Vapor Pressure: 6.997mmHg at 25°C
• Refractive Index: n20/D 1.409(lit.)
• BRN: 2204704
• CAS DataBase Reference: (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE(17510-46-2)
• EPA Substance Registry System: (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE(17510-46-2)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• F: 10-21
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 17510-46-2(Hazardous Substances Data)

Usage

Description

(2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE, also known as (1-tert-Butylvinyloxy)trimethylsilane, is a silyl enol belonging to the organosilicone class of compounds. It is characterized by its unique chemical structure and properties, which include an enthalpy of vaporization at boiling point.

Uses

Used in Pharmaceutical Industry:
(2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE is used as a synthetic intermediate for the synthesis of various pharmaceutical compounds. Its application is primarily due to its unique reactivity and stability, which allow for the creation of complex molecular structures with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE is used as a reagent for the synthesis of cis-3,3-dimethyl-1-(6-phenethyl-3,6-dihydro-2H-pyran-2-yl)butan-2-one. (2,2-DIMETHYL-1-METHYLENEPROPOXY)TRIMETHYLSILANE serves as a key intermediate in the development of novel chemical entities with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C9H20OSi/c1-8(9(2,3)4)10-11(5,6)7/h1H2,2-7H3

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 

Downstream Products

• 624-95-3 3,3-dimethylbutanol 
• 37471-41-3 3,3-dimethyl-1-(phenylthio)butan-2-one 
• 83467-62-3 C₃₂H₃₂O₈ 
• 75-77-4 chloro-trimethyl-silane 
• 93287-15-1 1-(2-oxo-1-pyrrolidinyl)-4,4-dimethyl-3-pentanone 
• 6721-67-1 tert-butyl benzyl ketone 
• 95546-33-1 1-hydroxy-4,4-dimethyl-1,1-diphenyl-pentan-3-one 
• 89867-80-1 (3-tert-Butyl-2,2-diphenyl-oxetan-3-yloxy)-trimethyl-silane 
• 93836-20-5 2-(2,3,5-tri-O-benzyl-α-D-ribofuranosyl)acetophenone 
• 93622-19-6 3,3-Dimethyl-1-(2-phenyl-1,3-dioxolan-2-yl)-2-butanon 
• 130496-70-7 (5S^*,1'R^*,3'S^*)-2,2-Dimethyl-5-(3'-hydroxy-1'-methylbutoxy)-5-phenylpentan-3-one 
• 130496-70-7 (5S^*,1'S^*,3'R^*)-2,2-Dimethyl-5-(3'-hydroxy-1'-methylbutoxy)-5-phenylpentan-3-one 
• 88222-65-5 3,3-dimethyl-1-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)-2-butanone 
• 88222-65-5 3,3-dimethyl-1-(2,3,5-tri-O-benzyl-α-D-ribofuranosyl)-2-butanone 

Relevant articles and documents

SUR L'OBTENTION HAUTEMENT REGIO- ET STEREOSELECTIVED'ENOXYSILANES PAR ACTION DU BIS(TRIMETHYLSILYL)ACETAMIDE EN MILIEU HMPT SUR LESS DERIVES CARBONYLES ENOLISABLES

The authors describe a new and general method for the preparation of enoxysilanes by silylation of enolizable aldehydes and ketones by use of bis(trimethylsilyl)acetamide in HMPT, in the presence of very small quantities of sodium metal(or another basic a