15588-95-1 Usage
Description
2,5-Dimethoxy-4-Methylamphetamine (DOM, STP) is a synthetic amphetamine derivative known for its dose-dependent psychotomimetic and hallucinogenic properties. It exhibits a strong affinity for serotonin 5-HT2 receptors, making it a compound of interest in various research and forensic applications. Classified as a Schedule I compound in the United States, DOM is primarily used for research purposes.
Uses
Used in Research and Forensic Applications:
2,5-Dimethoxy-4-Methylamphetamine is used as a research compound for studying the effects of its potent binding and activation of serotonin 5-HT2 receptors. This application aids in understanding the underlying mechanisms of its psychotomimetic and hallucinogenic properties, which can be valuable in the development of new therapeutic approaches for various psychiatric and neurological disorders.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,5-Dimethoxy-4-Methylamphetamine is used as a starting point for the development of new drugs targeting serotonin 5-HT2 receptors. Its interaction with these receptors provides insights into potential therapeutic applications, such as the treatment of depression, anxiety, and other mood disorders.
Used in Neuropharmacological Studies:
2,5-Dimethoxy-4-Methylamphetamine is used as a tool in neuropharmacological research to investigate the role of serotonin 5-HT2 receptors in the central nervous system. This helps researchers to better understand the complex interactions between neurotransmitters and their receptors, which can contribute to the development of more effective medications for a range of neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 15588-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,5,8 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15588-95:
(7*1)+(6*5)+(5*5)+(4*8)+(3*8)+(2*9)+(1*5)=141
141 % 10 = 1
So 15588-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H21NO2/c1-5-10-7-13(16-4)11(6-9(2)14)8-12(10)15-3/h7-9H,5-6,14H2,1-4H3
15588-95-1Relevant articles and documents
Stereospecific synthesis of amphetamines
Wagner, Jared M.,McElhinny Jr., Charles J.,Lewin, Anita H.,Carroll, F. Ivy
, p. 2119 - 2125 (2007/10/03)
Regioselective addition of aryl lithium to commercially available (S)-(+)-propylene oxide provides the corresponding (S)-aryl-2-propanol. The (R)-amphetamine is obtained by conversion of the alcohol to the tosylate followed by azide displacement and hydrogenation. Mitsunobu conversion of the alcohol to the (R)-bromide followed by azide displacement and hydrogenation affords the (S)-amphetamine.
The synthesis of four possible in vitro metabolites of the hallucinogen 1 (2,5 dimethoxy 4 methylphenyl) 2 aminopropane (DOM)
Coutts,Malicky
, p. 395 - 399 (2007/10/06)
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