609771-64-4

Basic information

• Product Name: 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl tosylate
• Synonyms: 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl tosylate
• CAS NO: 609771-64-4
• Molecular Weight: 364.463
• Mol File: 609771-64-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl tosylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl tosylate(609771-64-4)
• EPA Substance Registry System: 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl tosylate(609771-64-4)

Safety Data

• Hazardous Substances Data: 609771-64-4(Hazardous Substances Data)

Upstream product

• 13321-74-9 1-bromo-2,5-dimethoxy-4-methylbenzene 
• 24599-58-4 2,5-dimethoxy toluene 
• 38844-23-4 1-(2,5-dimethoxy-4-methylphenyl)-2-propanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 609771-65-5 1-(2,5-dimethoxy-4-methylphenyl)-2-propyl azide 
• 15588-95-1 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane 

Relevant articles and documents

Stereospecific synthesis of amphetamines

Regioselective addition of aryl lithium to commercially available (S)-(+)-propylene oxide provides the corresponding (S)-aryl-2-propanol. The (R)-amphetamine is obtained by conversion of the alcohol to the tosylate followed by azide displacement and hydrogenation. Mitsunobu conversion of the alcohol to the (R)-bromide followed by azide displacement and hydrogenation affords the (S)-amphetamine.