155911-16-3

Basic information

• Product Name: 6-HEX
• Synonyms: 2',4,4',5',7,7'-Hexachloro-3',6'-dihydroxy-3-oxo-3H-spiro-[isobenzofuran-1,9'-xanthene]-6-carboxy;2',4,4',5',7,7'-Hexachloro-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid;2',4,4',5',7,7'-Hexachloro-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid;2',4',5',7'-Tetrachloro-6-carboxy-4,7-dichlorofluorescein;Hexachloro-6-carboxyfluorescein;5(6)-HEX;2',4,4',5',7,7'-Hexachloro-3',6'-dihydroxy-3-oxo-3H-spiro-[isobenzofuran-1,9'-xanthene]-6-carb
• CAS NO: 155911-16-3
• Molecular Formula: C21H6Cl6O7
• Molecular Weight: 582.98614
• Mol File: 155911-16-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 794.8±60.0 °C(Predicted)
• Appearance: /
• Density: 2.06±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 1.61±0.20(Predicted)
• CAS DataBase Reference: 6-HEX(CAS DataBase Reference)
• NIST Chemistry Reference: 6-HEX(155911-16-3)
• EPA Substance Registry System: 6-HEX(155911-16-3)

Safety Data

• Hazardous Substances Data: 155911-16-3(Hazardous Substances Data)

Usage

General Description

6-HEX, also known as 6-hexanol, is a colorless liquid with a strong, sweet, herbaceous odor. It is a six-carbon alcohol with a molecular formula of C6H14O. 6-HEX is commonly used as a flavoring agent and fragrance ingredient in the food and cosmetic industry. It is also found in various essential oils, such as lavender and coriander. Additionally, 6-HEX has been identified as a volatile compound emitted from plants and is known to attract insects for pollination. In terms of safety, 6-HEX is considered to be relatively low in toxicity, but exposure to high concentrations may cause irritation to the eyes, skin, and respiratory system. Overall, 6-HEX plays a significant role in the creation of pleasant scents and flavors and is commonly utilized in a wide range of consumer products.

Upstream product

• 81742-10-1 3,6-dichloro-1,2,4-benzenetricarboxylic anhydride 
• 16606-61-4 2,4-dichlororesorcinol 

Downstream Products

• 1166837-63-3 2',4',5',7'-tetrachloro-6-carboxy-4,7-dichlorofluorescein dipivalate 

Relevant articles and documents

Synthesis, spectroscopic properties, and biological applications of eight novel chlorinated fluorescent proteins-labeling probes

Eight novel chlorinated fluorescent proteins-labeling probes with a linker and reactive group were prepared in 7 steps by the reaction of chlorinated resorcinols with 3, 6-dichloro-4-carboxyphthalic anhydride in the presence of methanesulfonic acid. Structures of target compounds and intermediates were determined via IR, MS, 1H NMR and element analysis. The spectral properties of the chlorinated fluoresceins were studied. These fluorescent probes showed absorbance peaks at 508-536 nm and fluorescence peaks at 524-550 nm. It was found that they have absorption and emission maxima at long wavelengths and high fluorescence quantum yields. Emission spectra of chlorinated fluoresceins shifted towards long wavelength with increase in chlorine. The probes were used for fluorescence imaging of cells in order to investigate whether they can conjugate to cells. The fluorescence imaging of living cells showed that they were localized in cell nucleus. However, they were localized in cytosol of chemically fixed cells. These probes will be useful reagents for the preparation of stable fluorescent conjugates.