15597-76-9

Basic information

• Product Name: 5-CHLOROSALICYLIDENE ANILINE
• Synonyms: 5-CHLOROSALICYLIDENE ANILINE;TIMTEC-BB SBB008052;4-Chloro-2-[(E)-(phenylimino)methyl]phenol;Phenol,4-chloro-2-(N-phenylformimidoyl)-;Phenol,4-chloro-2-[(phenylimino)methyl]-;2-(Phenyliminomethyl)-4-chlorophenol;4-Chloro-2-(N-phenylformimidoyl)phenol;4-Chloro-2-(phenyliminomethyl)phenol
• CAS NO: 15597-76-9
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.68
• Mol File: 15597-76-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 332.8°C at 760 mmHg
• Flash Point: 155.1°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.000142mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 5-CHLOROSALICYLIDENE ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLOROSALICYLIDENE ANILINE(15597-76-9)
• EPA Substance Registry System: 5-CHLOROSALICYLIDENE ANILINE(15597-76-9)

Safety Data

• Hazardous Substances Data: 15597-76-9(Hazardous Substances Data)

Usage

General Description

5-Chlorosalicylidene aniline is a chemical compound that belongs to the class of salicylidene anilines. It is a yellow solid with a molecular formula of C13H10ClNO2 and a molecular weight of 243.68 g/mol. 5-CHLOROSALICYLIDENE ANILINE is commonly used for the synthesis of azo dyes and metal complexes, and it also exhibits potential pharmacological and biological activities. It has been found to have antimicrobial and antifungal properties, as well as potential application in the development of drugs for various diseases. Its chemical structure and properties make it a versatile compound with potential applications in various fields, including pharmaceuticals, dyeing, and biotechnology.

InChI:InChI=1/C13H10ClNO/c14-11-6-7-13(16)10(8-11)9-15-12-4-2-1-3-5-12/h1-9,15H/b10-9-

Upstream product

• 62-53-3 aniline 
• 635-93-8 5-chlorosalicyclaldehyde 

Downstream Products

• 7123-49-1 4-chloro-2-(phenylaminomethyl)phenol 
• 51892-04-7 3,4-dihydro-3-phenyl-6-chloro-2H-1,3-benzoxazine 
• 155549-08-9 Cu(ClC₆H₃(O)CHNC₆H₅)2 
• 90759-54-9 Pt(OC₆H₃ClCHNC₆H₅)2 
• 1227260-62-9 6-chloro-N-phenyl-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromene-4-amine 
• 1227260-75-4 7-chloro-N-phenyl-2,3,4,4a,5,10a-hexahydropyrano[2,3-b]chromene-4-amine 
• 1323141-89-4 diethyl 5-chloro-3-(phenylamino)benzofuran-2,2(3H)-dicarboxylate 
• 1322617-87-7 N-(3-benzyl-6-chloro-2-oxo-4-(phenylamino)chroman-3-yl)benzamide 
• 1360873-56-8 (3aS,4R,9aR)-6-chloro-N-phenyl-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 
• 1026718-72-8 (3aR,4S,9aS)-6-chloro-N-phenyl-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 
• 84821-32-9 trans-bis(N-phenyl-5-chlorosalicylideneaminato)copper(II) 
• 1656994-69-2 Sodium dichloro-bis[N-phenyl-5-chlorosalicylideniminato-N,O]ruthenate(III) 

Relevant articles and documents

Copper-Catalyzed Asymmetric Annulation Reactions of Carbenes with 2-Iminyl- or 2-Acyl-Substituted Phenols: Convenient Access to Enantioenriched 2,3-Dihydrobenzofurans

We have developed a method for the highly diastereo- and enantioselective construction of 2,3-dihydrobenzofurans bearing tetrasubstituted carbon stereocenters by means of annulation reactions between carbenes and 2-iminyl- or 2-acyl-substituted phenols through catalysis by readily accessible copper(I)/bisoxazoline catalysts under mild conditions. These reactions feature a unique mechanism in which the copper catalyst serves a dual function: first it reacts with the diazo compound to generate a metal carbene, and second, upon formation of an oxonium ylide, it acts as a Lewis acid to activate the imine or ketone for diastereo- and enantioselective cyclization.

Synthesis and evaluation of copper complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted-benzenamine as selective inhibitors of protein tyrosine phosphatases

Five copper complexes, [Cu(bhbb,chbb,nhbb)(H2O)n] (tridentate-ligands: H2bhbb = 2-(5-bromo-2-hydroxylbenzylideneamino) benzoic acid, 1; H2chbb = 2-(5-chloro-2-hydroxylbenzylideneamino) benzoic acid, 2; H2/

Synthesis and evaluation of oxovanadium(iv) complexes of Schiff-base condensates from 5-substituted-2-hydroxybenzaldehyde and 2-substituted- benzenamine as selective inhibitors of protein tyrosine phosphatase 1B

Five oxovanadium(iv) complexes, which were divided into two groups, [V IVO(bhbb, nhbb)(H2O)2] (tridentate ligands: H2bhbb = 2-(5-bromo-2-hydroxylbenzylideneamino)benzoic acid, 1; H2nhbb = 2-(5-nitro-2