156774-70-8

Basic information

• Product Name: 2-phenylcyclopent-1-enecarboxylic acid methyl ester
• Synonyms: 2-phenylcyclopent-1-enecarboxylic acid methyl ester
• CAS NO: 156774-70-8
• Molecular Weight: 202.253
• Mol File: 156774-70-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenylcyclopent-1-enecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylcyclopent-1-enecarboxylic acid methyl ester(156774-70-8)
• EPA Substance Registry System: 2-phenylcyclopent-1-enecarboxylic acid methyl ester(156774-70-8)

Safety Data

• Hazardous Substances Data: 156774-70-8(Hazardous Substances Data)

Upstream product

• 934-56-5 trimethyl(phenyl)stannane 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 1830-92-8 methyl 2-oxocyclopentanecarboxylate 
• 65832-21-5 methyl 2-(trifluoromethylsulfonyloxy)cyclopent-1-enecarboxylate 
• 98-80-6 phenylboronic acid 
• 6638-68-2 4,5-dimethyl-2-phenyl-1,3,2-dioxaborolane 
• 132079-95-9 Methyl 2-<(Methanesulfonyl)oxy>cyclopentenecarboxylate 

Downstream Products

• 1380523-80-7 (2-phenylcyclopent-1-enyl)methanol 
• 1380523-81-8 (2-(bromomethyl)cyclopent-1-enyl)benzene 
• 1380523-82-9 dimethyl 2-((2-phenylcyclopent-1-enyl)methyl)malonate 
• 1380523-83-0 methyl 3-(2-phenylcyclopent-1-enyl)propanoate 
• 1380523-84-1 3-(2-phenylcyclopent-1-enyl)propan-1-ol 
• 1380523-85-2 3-(2-phenylcyclopent-1-enyl)propyl methanesulfonate 
• 1380523-37-4 dimethyl 2-(3-(2-phenylcyclopent-1-enyl)propyl)malonate 
• 207670-48-2 [4-(5H,11H-Pyrrolo-[2,1-c][1,4]benzodiazepine-10-carbonyl)-3-chloro-phenyl]-2-phenyl-cyclopent-1-enecarboxylic acid amide 
• 1616921-85-7 9-hydroxy-2-isopropyl-6-((1R,2S)-2-phenylcyclopentyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione 
• 1616921-86-8 9-hydroxy-2-isopropyl-6-((1S,2R)-2-phenylcyclopentyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione 
• 156774-71-9 2-phenyl-cyclopent-1-enecarboxylic acid 

Relevant articles and documents

PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE

The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.

QSAR studies and pharmacophore identification for arylsubstituted cycloalkenecarboxylic acid methyl esters with affinity for the human dopamine transporter

Data from a series of 29 monoamine transport inhibitors were used to generate 2D and 3D QSAR models for their binding affinity to the human dopamine transporter (hDAT). Among the inhibitors were many non-nitrogen containing compounds. The 2D QSAR analysis resulted in the equation -log Ki = 4.00 - 3.93ELUMO - 0.67EHOMO - 3.24σp, which predicted the importance of electron withdrawing groups in the aromatic moiety. However, the model failed to predict the observed poor binding of nitro-substituted compounds. In contrast, a derived 3D QSAR model was capable of predicting these more correctly.

Preparation of benzopyranylpropenamides for treatment of ischemia and arrhythmia.

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