157070-35-4

Basic information

• Product Name: (R)-2-Methyl-3-((S)-toluene-4-sulfinyl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine
• Synonyms: (R)-2-Methyl-3-((S)-toluene-4-sulfinyl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine
• CAS NO: 157070-35-4
• Molecular Weight: 277.387
• Mol File: 157070-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-Methyl-3-((S)-toluene-4-sulfinyl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Methyl-3-((S)-toluene-4-sulfinyl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine(157070-35-4)
• EPA Substance Registry System: (R)-2-Methyl-3-((S)-toluene-4-sulfinyl)-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine(157070-35-4)

Safety Data

• Hazardous Substances Data: 157070-35-4(Hazardous Substances Data)

Upstream product

• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 157070-41-2 1-Methyl-4-((S)-prop-1-yne-1-sulfinyl)-benzene 
• 4801-58-5 N-hydroxypiperidine 

Downstream Products

• 2858-66-4 (-)-pelletierine 

Relevant articles and documents

Synthesis of enantiomeric β-amino ketones via 1,3-dipolar cycloaddition and chromatographic resolution

The cycloaddition reactions of 3,4,5,6-tetrahydropyridine 1-oxide 1 with the homochiral alkynyl sulfoxides 6a-e proceed in high yield to afford, with low asymmetric induction, mixtures of diastereomeric isoxazolines that are readily separated by column chromatography.The resolved isoxazolines can be subsequently converted, by hydrogenolysis, to enantiomeric β-amino ketones.