157547-47-2Relevant articles and documents
A facilitated cyclic ether formation and its potential application in solid-phase peptide and organic synthesis
Shan, Daxian,Zheng, Ailian,Ballard, C. Eric,Wang, Wei,Borchardt, Ronald T.,Wang, Binghe
, p. 238 - 244 (2007/10/03)
A 'trimethyl lock' system has been known to facilitate lactonization reactions through what has been termed a stereopopulation control mechanism. We have found that a similar trimethyl lock system can also facilitate cyclic ether formation with the concom
Phosphonooxy and carbonate derivatives of taxol
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, (2008/06/13)
The present invention is directed to novel taxol derivatives useful as anti-tumor agents. Also provided by this invention is pharmaceutical formulations and methods of treating mammalian tumors with the compounds of this invention.