15757-32-1

Basic information

• Product Name: 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-1-methyl-3-phenyl-
• Synonyms: N-methyl-3-phenyl-3-hydroxyoxindole;3-hydroxy-1-methyl-3-phenyl-1,3-dihydro-2H-indol-2-one;3-hydroxy-1-methyl-2-oxo-3-phenyl-2,3-dihydroindole;3-hydroxy-1-methyl-3-phenyl-oxindole;3-hydroxy-1-methyl-3-phenylindolin-2-one;2H-Indol-2-one,1,3-dihydro-3-hydroxy-1-methyl-3-phenyl;3-hydroxy-1-methyl-3-phenyl-1,3-dihydroindol-2-one
• CAS NO: 15757-32-1
• Molecular Formula: C15H13NO2
• Molecular Weight: 239.274
• Mol File: 15757-32-1.mol
• Article Data: 30

Chemical Properties

• Melting Point: 141-143 °C
• Boiling Point: 490.1±45.0 °C(Predicted)
• Density: 1.288±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-1-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-1-methyl-3-phenyl-(15757-32-1)
• EPA Substance Registry System: 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-1-methyl-3-phenyl-(15757-32-1)

Safety Data

• Hazardous Substances Data: 15757-32-1(Hazardous Substances Data)

Upstream product

• 579-75-9 2-Methoxybenzoic acid 
• 103-67-3 benzyl-methyl-amine 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 113737-84-1 3-hydroxy-1-methyl-3-phenylquinoline-2,4(1H,3H)-dione 
• 32119-53-2 N-methyl-N-phenacylaniline 
• 133363-43-6 N-methyl-2-(1-phenylethenyl)benzenamine 
• 64097-92-3 2-(1-phenylvinyl)aniline 
• 3335-97-5 1-methyl-3-phenylindolin-2-one 
• 64605-29-4 1-(2-(methylamino)phenyl)-2-phenylethanone 
• 98-80-6 phenylboronic acid 
• 1285240-21-2 N-(2-bromophenyl)-2-oxo-2-phenylacetamide 
• 91-56-5 indole-2,3-dione 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 1215299-39-0 C₁₅H₁₄N₂O 
• 1351204-45-9 (R)-3-((R)-1-(benzyloxy)allyl)-1-methyl-3-phenylindolin-2-one 
• 866993-97-7 1-methyl-3-(2-nitrophenoxy)-3-phenyl-1,3-dihydroindol-2-one 
• 866993-99-9 3-(2-hydroxy-5-methylphenyl)-1-methyl-3-phenyl-1,3-dihydroindol-2-one 
• 1334682-33-5 C₁₅H₁₃NO₂ 

Relevant articles and documents

Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.

Visible light mediated aerobic oxidative hydroxylation of 2-oxindole-3-carboxylate esters: An alternative approach to 3-hydroxy-2-oxindoles

A convenient aerobic oxidative hydroxylation of 3-substituted oxindoles under mild reaction conditions is described herein. This process was accomplished by the activation of molecular oxygen in the air in the presence of a photocatalyst under the irradiation of visible light. The desired product was delivered in up to 89% yield without the addition of base or stoichiometric oxidant.

Palladium-catalyzed selective synthesis of 3-hydroxy-2-oxindoles via cascade C-H cycloaddition and oxidation of α-Aminoacetophenones

A novel method for the synthesis of 3-hydroxy-2-oxindole (3-hydroxyindolin-2-one) derivatives by palladium-catalyzed tandem C-H cycloaddition and oxidation of α-Aminoacetophenone has been developed. In the presence of Pd(OAc)2 and AgOAc, a variety of 3-hy