32119-53-2

Basic information

• Product Name: Ethanone, 2-(methylphenylamino)-1-phenyl-
• CAS NO: 32119-53-2
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 32119-53-2.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(methylphenylamino)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(methylphenylamino)-1-phenyl-(32119-53-2)
• EPA Substance Registry System: Ethanone, 2-(methylphenylamino)-1-phenyl-(32119-53-2)

Safety Data

• Hazardous Substances Data: 32119-53-2(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 100-61-8 N-methylaniline 
• 172983-93-6 2-[(2-Iodo-phenyl)-methyl-amino]-1-phenyl-ethanone 
• 121-69-7 N,N-dimethyl-aniline 
• 98-88-4 benzoyl chloride 
• 93-61-8 N-methyl-N-phenylformamide 
• 36602-08-1 (N-methylanilino)acetonitrile 
• 100-58-3 phenylmagnesium bromide 
• 181265-77-0 2-bromoacetophenone t-butoxycarbonyl hydrazone 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 100-42-5 styrene 
• 172984-02-0 N-(2-iodoanilinomethyl)succinimide 
• 57056-93-6 N-methyl-2-iodoaniline 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 16056-11-4 N,N,N-trimethylanilinium bromide 
• 948-65-2 2-phenyl-indole 
• 4636-16-2 iodoacetophenone 
• 98-04-4 phenyltrimethylammonium iodide 
• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 30020-98-5 N-methyl-3-phenylindole 
• 33192-08-4 4-(methylamino)phenyl thiocyanate 
• 106345-32-8 2‐phenyl‐3‐(phenylthio)‐1H‐indole 

Relevant articles and documents

Stevens rearrangement of anilinium salts by the action sodium carbonate hexahydrate

Anilinium salts containing an allyl-like group together with various functionally substituted receiving groups undergo Stevens rearrangement by the action of sodium carbonate hexahydrate in the absence of a solvent. As a result, both N-methylaniline deriv

Iron-catalyzed reductive strecker reaction

Strecker reaction is widely applied for the synthesis of amino acids from aldehydes, amines and cyanides. Herein, we report the FeI2-catalyzed reductive Strecker type reaction of formamides instead of aldehydes to produce amino acetonitriles. The challenging capture of carbinolamine intermediates by CN? was achieved via Fe catalysis. This approach afforded better yields than the use of Ir- or Rh-catalysts. The application ability of this methodology is demonstrated by 1) one-pot construction of (13C labeled) complex molecules from CO2 via amino acetonitrile intermediates and 2) convenient production of homologated carboxylic acids from aldehydes.

Solvent-Free Synthesis of α-Amino Ketones from α-Hydroxyl Ketones via A Novel Tandem Reaction Sequence Based on Heyns Rearrangement

Heyns rearrangement have been famous for carbohydrate chemists for several decades. However, this reaction was underrated as a useful method for synthetic chemists due to preparative shortcomings. Herein we developed an efficient method for the synthesis of pharmaceutically important α-amino ketones from readily available α-hydroxy ketones and secondary amines through a tandem reaction sequence based on Heyns rearrangement. The reaction smoothly proceeded by using catalytic PTSA as catalyst without solvent. Primary and secondary α-hydroxy ketones were readily used and regioselectively afforded the correspondingly α-amino ketones with moderate yield.