15762-14-8Relevant articles and documents
Potential Inhibitors of Phosphoenolpyruvate (PEP) Carboxylase: Phosphonic Acid Substrate Analogues Derived from Stobbe-Type Condensations of Ethyl 3-(Diethoxyphosphinoyl)propanoate
McFadden, Helen G.,Harris, Roger L. N.,Jenkins, Colin L. D.
, p. 1619 - 1629 (2007/10/02)
Phosphonic acid analogues of 2-(dihydroxyphosphinoyloxy)propenoic acid (PEP), the substrate of PEP carboxylase, were prepared and tested as inhibitors of the enzyme.The required triacids were obtained by mild hydrolysis of the partial esters prepared by S